Lung Function in Sudanese Children and Adolescents with Type 1 Diabetes Mellitus
Journal Title: Journal of Advances in Medicine and Medical Research - Year 2016, Vol 16, Issue 3
Abstract
Background: Diabetes Mellitus Type 1 (DMT1) is a chronic, debilitating and multifactor disease that is emerging as an important health problem in Sudan. The aim of this study was to investigate the lung functions in Sudanese children and adolescents as well as to explore the effects of duration, age, gender and insulin dose on the pulmonary functions. Methods: This is a hospital-based controled study conducted in the diabetic center of Wad Madani Pediatrics Hospital. A total of 80 males and 80 females with DMT1 and matching healthy controls were included. Spirometry was performed on a microspirometer (compact hand instrument, Switzerland, 2000). Results: Our data revealed that children with diabetes showed significantly lower mean values of Forced Expiratory Volume in First Second (FEV1), Forced Vital Capacity (FVC) and Peak Expiratory Flow Rate (PEFR), except the ratio FEV1/FVC that has shown a significant increase compared with the healthy controls. Male patients with diabetes demonstrated a greater increase in FEV1, FVC and PEFR than the females, but the ratio FEV1/FVC was increased in both equally and significant correlations between FEV1, FVC, PEFR and age, gender, duration dose of insulin were found in patients with diabetes. Conclusion: The actual lung function data among Type 1 diabetic children and adolescents showed significantly lower values of FVC, FEV1, and PEFR with increased FEV1 and FVC compared to the predicted lung function data which indicated a restrictive pattern.
Authors and Affiliations
Omer M. Al Tayeb, Hiba A. Awooda, Aisha M. Bello
Keywords
Related Articles
- EP ID EP341270
- DOI 10.9734/BJMMR/2016/26378
- Views 65
- Downloads 0
Biologics and Biosimilars: Differences and Clinical Implications
Biologics or biopharmaceuticals are drugs derived from living organisms by recombinant technology. Biologics have made a significant contribution to the management of certain chronic diseases such as cancer, rheumatoid,...
Mild Hypothermia Attenuates the Excitatory Amino Acids Overflow and Diminishes the Nitric Oxide Synthase Activity during Reperfusion after Asphyxial Cardiac Arrest in Rats
Aims: Neurotransmitter overflow into the extracellular space and activation of nitric oxide synthase were implicated in neuronal death after cerebral ischemia. A small temperature reduction induced after the insult cruci...
Nosocomial Infection in the Neonatal Ward of a Tertiary Care Hospital: The Role of Active Surveillance in the Control of Klebsiella pneumoniae Outbreak
Aim: To describe an outbreak which occurred in a neonatal ward and the role of active surveillance in the control of further outbreaks. Study Design: Cross Sectional Observational Study. Place and Duration of Study: Lady...
Steatocystoma Multiplex Limited to the Vulva: Report of a Very Rare Case Successfully Treated by a Simple Surgical Method
Aim: Steatocystoma multiplex (SM) is a rare malformation characterized by multiple cutaneous cystic lesions containing oily substance. SM has autosomal dominant mode of inheritance, though there are a significant number...
Influence of Diabetes Mellitus on Stroke
Diabetes is known to be an independent risk factor for the development of stroke. Stroke accounts for 20% of deaths among patients with diabetes, and is seen more commonly in younger age group than in non-diabetics. This...