MAGNITUDE AND DETERMINANTS OF RESTLESS LEGS SYNDROME IN PATIENTS WITH CHRONIC KIDNEY DISEASE ADMITTED IN A RURAL TERTIARY CARE HOSPITAL
Journal Title: PARIPEX-Indian Journal of Research - Year 2017, Vol 6, Issue 12
Abstract
Background: Restless legs syndrome (RLS) is a common and extremely distressing problem experienced by chronic kidney disease (CKD) patients. RLS is also associated with poor sleep, impaired quality of life, increased incidence of cardiovascular events and higher mortality in CKD patients. Settings and Design: A cross-sectional hospital-based study was performed in CKD patients admitted in the department of Medicine of a rural teaching tertiary care hospital in central India. Materials and Methods: In all consecutive CKD inpatients, presence of RLS or its severity was assessed by a trained person through a questionnaire [International Restless Legs Syndrome Study Group (IRLSSG) criteria] who is blind of the comorbidities and investigations of the patient. Another study person collected the data including demographics, co-morbid diseases or risk factors, clinical and laboratory parameters. Results: Of the total 206 CKD patients, 143 (69%) were males and 63 (31%) were females. Forty-eight (23%) of the 206 CKD patients had RLS. Of the 206 CKD patients, 4 (1.9%) had mild RLS, 15 (7.3%) had moderate RLS, 18(8.7%) had severe RLS and 11(5.3%) had very severe RLS. The association of female gender, hemodialysis, severe anemia and serum ferritin level with RLS was found to be statistically significant (P < 0.05). Conclusion: RLS was present in 23% (approximately one quarter) of patients with CKD and was related to female gender, hemodialysis, severe anemia and serum ferritin levels.
Authors and Affiliations
Dr Amrish Saxena
Keywords
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