Malignant Hepatic Lesions: Ct, Biochemical and Pathologic Findings in Northeast India
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 6
Abstract
Hepatic Space Occupying Lesions (SOLs) are increasingly being detected due to the widespread use of imaging modalities.It is important to label the lesion as benign or malignant.It is also essential to categorise the malignant lesion as primary or secondary.Knowledge of the underlying key pathologic features with biochemical indices and imaging findings of liver masses on MDCT(MultidetectorComputed Tomography) allows characterization in most cases. Some masses, however, may exhibit overlapping and nonspecific radiologic features, and in such cases percutaneous image-guided biopsy may become necessary. This study was performed to review the CT characteristics of malignant hepatic lesions with biochemical and pathological correlation.61patients who underwent contrast CT with a 128-slice CT scanner were included. The precontrast,late arterial,portal venous phase and equilibrium phase were evaluated with biochemical and histopathological correlation.22 patients belonged to non-tribal population while 39 were tribals from Northeast India.The age ranged from 16-80 years and 22 patients were females.31 patients had hepatic metastases from various primaries,27 patients had Hepatocellular carcinoma,2 patients had primary hepatic neuroendocrine cancer(PHNEC) and one had desmoplastic round cell tumour. The imaging characteristics on multiphase contrast-enhanced CT in combination with clinical and biochemical correlation allows noninvasive characterization of most liver lesions comparable to MRI. It also has an added advantage of detecting primary extrahepatic tumor and allows proper staging.
Authors and Affiliations
Dr. Baphiralyne Wankhar, Dr. Caleb Harris, Dr. Kyrshanlang G Lynrah, Dr. Prem Pradeep Batchala, Dr. Bifica Sofia Lyngdoh
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