MAT (MULTIFOCAL ATRIAL TACHYCARDIA) IN DIGOXIN TOXICITY
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2017, Vol 4, Issue 9
Abstract
BACKGROUND In 1785, Withering discovered use of a cardiac glycoside from foxglove plant for the therapy of congestive heart failure. For centuries, digoxin use had been controversial for the risk benefit ratio. Digoxin affect the myocardium by affecting the autonomic nervous system. Antiadrenergic and parasympathetic stimuli suppressing SA node, but delayed after depolarisation of atrial muscles causes generation of multiple atrial pacemaker foci presenting in the form of MAT. The association of MAT with digoxin is poorly studied because of the rarity of both together. This case had multiple risk factor of advanced age, hypokalaemia, heart failure in presence of chronic digoxin exposure caused MAT. Withdrawal of digoxin along with correction of electrolyte imbalance and heart failure caused reversal of MAT to sinus rhythm. Early detection
Authors and Affiliations
Pranav Tyagi, Madhugandha Wahane, Arif Mohammad
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