Measles virus: a perpetual challenge
Journal Title: Indian Journal of Research in Pharmacy and Biotechnology - Year 2015, Vol 3, Issue 3
Abstract
Measles is a highly contagious respiratory virus infection, with typical clinical symptoms including maculopapular rash, fever, cough, coryza, and conjunctivitis. Measles is highly contagious 90% of people who haven't been vaccinated for measles will get it if they are near an infected person and is one of the leading causes of death in children fewer than 5 years of age worldwide. The WHO aims, to reduce the overall mortality rate in under-5 year-olds by two-thirds between 1990 and 2015. Measles virus is a member of the Morbillivirus genus of the Paramyxoviridae family. Measles is a highly transmissible and irritating disease, which usually affects children. The highly contagious virus is spread by coughing and sneezing, close personal contact or direct contact with infected nasal or throat secretions. Measles also can be confirmed by isolating measles virus in cell culture from respiratory secretions, nasopharyngeal and conjunctival swabs, blood, or urine. No specific antiviral treatment exists for measles virus. Severe complications from measles can be avoided through supportive care that ensures good nutrition, adequate fluid intake and treatment of dehydration with WHO-recommended oral rehydration solution. This solution replaces fluids and other essential elements that are lost through diarrhea or vomiting. Antibiotics should be prescribed to treat eye and ear infections, and pneumonia.
Authors and Affiliations
Suresh Rewar
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