Mechanisms of action of activated pyrithione zinc
Journal Title: Український журнал дерматології, венерології, косметології - Year 2018, Vol 0, Issue 4
Abstract
Activation of zinc pyrithione gives it complementary pharmacodynamic properties — antimicrobial and antifungal effects, which determine its effectiveness in psoriasis and atopic dermatitis. The use of Skin-cap in these diseases is accompanied by the activation of apoptosis of cells of the lower layers of the epidermis and cells-effectors of allergic inflammation. The level of neutrophils and lymphocytes in the skin also decreases. The results of randomized controlled studies indicate a high efficacy of this drug in atopic dermatitis and psoriasis. Due to a wide range of pharmacological activity and clinical experience, Skin-cap is recognized as a safe non-steroid drug for external therapy. This allows recommending it for use in dermatology, pediatrics and allergology.
Authors and Affiliations
N. Е. Kostinska, G. B. Kostinskiy
Keywords
Related Articles
- EP ID EP455039
- DOI 10.30978/UJDVK2018-4-53
- Views 103
- Downloads 0
Verrucous psoriasis: clinical case
Case of rare clinical form of psoriasis — verrucous psoriasis — is described. Diagnostic mistakes and results of differential diagnostics are presented.
Quality of life in acne patients with Demodex folliculorum and Demodex brevis mites in areas of affected skin
Objective — to compare the quality of life in acne patients with and without detected Demodex folliculorum and Demodex brevis in affected skin. Materials and methods. We studied 105 patients with acne for the presence o...
Application of Teobon-dithiomycocide for treatment of fungal diseases of feet complicated by hyperkeratosis
Today, almost 30 % of the world’s population suffers from mycoses, of which the most common are mycoses of the feet. The treatment of mycoses complicated by hyperkeratosis is a difficult problem. Objective — to determin...
How oral collagen intake can be useful in dermatology
Collagen is the main component of dermis. It represents as much as 75 % of dry skin weight. With aging, collagen content decreases in the skin, because of a reduced production by the fibroblasts and higher metabolism rat...
Rational approach to choice of topical therapy of patients with onychomycosis
Objective — to increase the efficacy of treatment of patients with onychomycosis by appointing topical therapy with Onychocid® Emtrix complex. Materials and methods. The analysis of modern research on the prevalence of...