MECONIUM-STAINED AMNIOTIC FLUID AND MECONIUM ASPIRATION SYNDROME- A STUDY ON RISK FACTORS AND NEONATAL OUTCOME
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 70
Abstract
BACKGROUND Meconium is the first faeces of a newborn. Meconium-stained amniotic fluid (MSAF) occurs in about 7-22% of live births and is regarded as a sign of foetal compromise. Meconium aspiration syndrome (MAS) is a serious and potentially preventable condition with risk factors like post-dated pregnancy, small for gestational age, oligohydramnios, hypertensive disorder of pregnancy, gestational diabetes, and maternal drug abuse. Hence, the present study was conducted to find out the rate of MAS, analyse associated maternal and neonatal risk factors and final outcome in babies born through MSAF in a tertiary health care facility. Objectives- 1. To find out the rate of Meconium aspiration syndrome (MAS) in babies born with Meconium-stained amniotic fluid (MSAF) in a tertiary health care facility, GGH, Guntur. 2. To analyse the associated maternal and neonatal risk factors associated with Meconium aspiration syndrome (MAS). 3. To evaluate the outcome of Meconium aspiration syndrome (MAS). MATERIALS AND METHODS A prospective, hospital based, observational study was carried out among 160 babies born with MSAF admitted to the NICU in a tertiary health care setting in the Department of Paediatrics, during a period of 5 months. Patient details were recorded in a predesigned semi-structured proforma. Informed written consent was taken from parents of babies. MAS was designated in a baby as per the defined criteria. Their risk factors and outcomes were analysed by using SPSS Software 18 version. Institutional ethics committee approval was obtained. RESULTS Out of the total 160 babies born with MSAF, 68 (42.5%) were female and 92 (57.5%) were male. MAS was seen in 21 (13.12%) babies. It was observed that there is significant association between MAS & MSAF and the following risk factors like Post maturity (1.25%), Small for Gestational Age (SGA) (11.25%), Oligohydramnios (4.38%) and low APGAR (5.62%). MAS babies who required ventilation (CPAP & IMV) were 9 (42.85%). The mortality observed in our study was 5 (23.80%), and the rest of the 16 MAS babies were discharged without any complications. CONCLUSION MSAF and MAS affect mostly full term and post-term babies. MAS has significant effect on neonatal outcome when it is associated with risk factors like post-term gestation, SGA, Oligohydramnios, APGAR score < 7. These babies required ventilator support, hence they require continuous and close monitoring in a tertiary care setting. MSAF and MAS can be prevented by appropriate antenatal and natal care by the obstetrician and neonatologist.
Authors and Affiliations
Thirupathi Reddy Avula, Suneetha Bollipo
Keywords
Related Articles
- EP ID EP233437
- DOI 10.14260/Jemds/2017/1079
- Views 96
- Downloads 0
COMPARATIVE STUDY BETWEEN CONVENTIONAL CLINICAL EXAMINATION (CCE) V/S OBJECTIVE STRUCTURED CLINICAL EXAMINATION (OSCE) AS AN EVALUATION TOOL FOR MBBS STUDENTS
[b]BACKGROUND[/b]: In India, there has been a considerable rethink on the curriculum of medical education, specially, on the teaching and assessment methodology. Subjective assessment is slowly giving way to o...
PANCREATICO DUODENAL NEUROENDOCRINE TUMOURS – OUR EXPERIENCE OVER THE PAST 2 YEARS
[b] INTRODUCTION[/b]: Pancreaticoduodenal Neuroendocrine tumours are a heterogeneous group of tumours with their origin in neuroendocrine cells of the embryological gut which are positive for ‘Pan-neuroendocri...
INCIDENTAL FINDING OF BRUNNER GLAND HYPERPLASIA IN A CASE OF GASTRIC ADENOCARCINOMA
This case of ours is a 70year old male patient who presented with gastric outlet obstruction. Endoscopy revealed nodular ulcerated mass lesion involving 3/4th of the circumference noted in the distal body of stomach...
ROLE OF FINE NEEDLE ASPIRATION CYTOLOGY IN BREAST LESIONS
BACKGROUND FNAC is a relatively simple procedure with good patient acceptance and low morbidity. It is an accurate, safe and repeatable procedure in the diagnosis of various breast lesions- both malignant and non-maligna...
STUDY OF DENGUE FEVER BETWEEN INFANTS (≤1 YEAR) AND OLDER CHILDREN (>1 YEAR) IN A TERTIARY CARE HOSPITAL
BACKGROUND Dengue fever has been a common and fatal vector borne disease in tropical countries and is found to be present throughout the year and also to occur in epidemics. There has been very little information on deng...