MEDICINAL USES, BIOLOGICAL AND CHEMICAL PROPERTIES OF WILD GRAPE (LANNEA EDULIS): AN INDIGENOUS FRUIT PLANT OF TROPICAL AFRICA
Journal Title: Asian Journal of Pharamceutical and Clinical Research - Year 2019, Vol 12, Issue 9
Abstract
Lannea edulis is a fruit plant widely used as herbal medicine throughout its distributional range in tropical Africa. This study was aimed at providing a critical review of the biological activities, phytochemistry, and medicinal uses of L. edulis. Documented information on the botany, biological activities, medicinal uses, and phytochemistry of L. edulis was collected from several online sources which included BMC, Scopus, SciFinder, Google Scholar, Science Direct, Elsevier, PubMed, and Web of Science. Additional information on the botany, biological activities, phytochemistry, and medicinal uses of L. edulis was gathered from pre-electronic sources such as book chapters, books, journal articles, and scientific publications sourced from the University library. This study showed that the bark, leaves, rootbark, and roots of L. edulis are used as antiabortifacient and herbal medicine to dilate birth canal, dizziness, sore eyes, sexually transmitted diseases, amenorrhea and dysmenorrhea, malaria, bilharzia, and gastrointestinal problems. Ethnopharmacological research revealed that L. edulis extracts and compounds have anthelmintic, anti-human immunodeficiency virus, antihyperglycemic, antihyperlipidemic, antimalarial, antimicrobial, antioxidant, and cytotoxicity activities. Future studies should focus on conducting detailed phytochemical, pharmacological, and toxicological evaluations of L. edulis crude extracts as well as compounds isolated from the species.
Authors and Affiliations
ALFRED MAROYI
STABILITY-INDICATING REVERSE-PHASE HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY METHOD FOR THE SIMULTANEOUS QUANTIFICATION OF APIGENIN AND LUTEOLIN FROM ACHILLEA MILLEFOLIUM LINN
Objective: A stability-indicating reverse-phase high-performance liquid chromatographic method was developed and validated for the analysis of apigenin and luteolin. The degradation behavior of apigenin and luteolin was...
RESPONSES OF BRAIN TISSUES AGAINST HYPOXIC CONDITION IN HEMORRHAGIC STROKE PATIENTS: NEUROGLOBIN EXPRESSION IN BRAIN TISSUE AND PLASMA
Objective: Strokes remain a significant health concern and are the highest cause of mortality and physical or mental disability in productive and the elderly hospitalized patients in Indonesia. Neuroglobin (Ngb) mostly l...
IN VITRO CYTOTOXICITY ACTIVITY OF HYDROALCOHOLIC EXTRACT OF POLYHERBAL CHURNAM (COFRI) IN NORMAL LIVER AND KIDNEY CELL LINES
Objective: The objective of the study was to investigate the cytotoxic activity of hydroalcoholic extract of a polyherbal powder on Vero (normal kidney) and Chang (normal liver) cell lines. Methods: The cytotoxic effect...
A STUDY ON PATIENTS’ AWARENESS, RECOGNITION MANAGEMENT AND PREVALENCE OF HYPOGLYCEMIC EPISODES IN TYPE 2 DIABETES MELLITUS IN A TERTIARY CARE HOSPITAL
Objective: To assess patients’ awareness on management of hypoglycemic episodes and analyzing the prevalence of hypoglycemic episodes inpatients with Type 2 diabetes mellitus.Methods: A prospective-observational compar...
DEVELOPMENT AND OPTIMIZATION OF ENZALUTAMIDE-LOADED SOLID LIPID NANOPARTICLES USING BOX–BEHNKEN DESIGN
Objective: The primary motive behind this investigation is to develop and optimize the solid lipid nanoparticles formulation of enzalutamide for the effective drug delivery. Materials and Methods: The formulation variab...