Metabolic syndrome as a risk factor for ischemic stroke
Journal Title: Moldovan Medical Journal - Year 2017, Vol 60, Issue 1
Abstract
Background: Ischemic stroke is the leading cause of disability and a major cause of mortality worldwide. It is predominantly seen in the elderly and in patients with the metabolic syndrome (MS) [1, 2]. Material and methods: A “case-control” study was performed on 125 subjects with ischemic stroke and on 300 subjects without stroke. After the patients or their relatives signed an informed written consent, according to the declaration of Helsinki, the baseline data was collected by questionnaire. All subjects underwent a complete clinical examination and ultrasound examination of the extracranial carotids. Ischemic stroke diagnostic was made by a neurologist and confirmed by a brain CT scan. MS diagnostic was made according to the diagnostic criteria of the American Cardiology Association (AHA), the National Heart, Lung and Blood Institute (NHLBI) and the International Diabetes Federation (IDF) (2009). Results: Fifty-four percent of patients and 36% of controls had metabolic syndrome criteria according to AHA, NHLBI, IDF (OR: 2.1; CI (1.1, 3.1), p=0.05). The prevalence of atherosclerotic plaques at the level of the extracranial carotid section was significantly higher in patients with stroke compared to the control group (67.2 % vs. 20,0%). Conclusions: In our study generally metabolic syndrome was higher in stroke patients but different components of this syndrome were significantly high either. So management of individual components of the metabolic syndrome is recommended, including lifestyle measures (exercise, appropriate weight loss, proper diet) and pharmacotherapy (medications for BP lowering, lipid lowering, glycemic control, and antiplatelet therapy).
Authors and Affiliations
Natalia Ciobanu, Stanislav Groppa
Keywords
Related Articles
- EP ID EP484104
- DOI 10.5281/zenodo.1050329
- Views 187
- Downloads 0
Management of the aesthetic medicine services in the Republic of Moldova
Background: In recent years, there has been an increasing interest in aesthetic medicine. Minor-invasive or injectable procedures, as well as laser therapy have become extremely successful. In case of any inherited or ac...
Fungal rhinosinusitis: pathophysiology, diagnosis and treatment
Background: Fungal rhinosinusitis is a major clinical problem which should be considered in all patients and immunocompromised patients with chronic rhinosinusitis. It may be non-invasive or invasive with five main subty...
B-cell lymphoma-2 receptor in human primary breast and its lymph node metastases: more than a surrogate marker
Background: Due to its anti-apoptotic and anti-proliferative contradictory functions, BCL2 role in breast carcinoma progression is not clearly understood. The purpose of this study was to highlight BCL2 expression during...
Coffee consumption influence upon the clinico-neurophysiological manifestations of primary sleep bruxism
Background: Caffeine is one of the most widely-used psychoactive substances, having multiple stimulating effects. Caffeine is being considered as eliciting a dose-dependent effect on sleep bruxism. Material and methods:...
Hard palate in fetal and early neonatal periods of human ontogenesis
Background: This investigation is important to reveal hard palate ontogenetic transformations in fetal and early neonatal periods, which is important for the facial surgery in fetuses, newborns. Material and methods: Inv...