Methotrexate a Double Edged Sword – Effect of Methotrexate in patients of Psoriasis due to Medication Errors
Journal Title: International Journal of Current Research and Review - Year 2017, Vol 9, Issue 20
Abstract
Methotrexate is one of the most commonly used anti-neoplastic and disease modifying drug today. Side effects of methotrexate at high dose may be life threatening; however, these side effects oral dosing are variable because of the inter-individual variability of gastrointestinal absorption of this drug. Because of confusing nature of its dosing schedule and different routes of administration there are high chances of misinterpretation of prescription. Medication errors involving methotrexate revealed that errors occurred during all phases of use, often resulted from confusion about dosage, and often caused death or other serious adverse effects. Here we present three cases of toxicity due to methotrexate medication error. All cases presented with multiple erosions and ulcers on skin and mucous membrane, organ failures, bone marrow suppression.
Authors and Affiliations
Dr. Vidya Kharkar
Keywords
Related Articles
- EP ID EP607599
- DOI 10.7324/IJCRR.2017.9203
- Views 131
- Downloads 0
Change in Urban Landuse and its Effect on Natural Drainage System: A Geographical Micro Leveled Study of Bhosari Stream (PCMC)
Horizontal and vertical expansion of urban areas has been increasing the rate of exploitation of natural resources, systems and their processes. Now a day, urban landuse has also been changing drastically and primarily a...
Studies on In-Vitro Interaction of Artemether-Lumefantrine with Food Components
This work evaluates in vitro interaction of food components with artemether–lumefantrine (AL) in tablet. Pelletized food components (i.e., starch, albumin, sunflower oil and carbonated drink) with AL tablet were observed...
Prevalence of Inducible Clindamycin Resistance of Staphylococcus aureus in Hospitalized Patients in Tertiary Care Hospital
Background: Methicillin resistant Staphylococcus aureus (MRSA) has emerged as one of the most common pathogen isolated from patients with very few drugs available for their treatment. Clindamycin is a good alternative op...
Association of Physical Activity and Complications of Diabetes among Patients Having Type 2 Diabetes Miletus
Objective: To assess the physical activities and complications of diabetes among patients having type 2 diabetes mellitus (T2DM). Methods: We conducted a cross-sectional study inpatients having (T2DM) to measure the effe...
Characterization of Gem and Abrasive Variety Corundum from Wyra Area of Khammam Schist Belt, Telangana, India, Using Advanced Spectroscopic Techniques
Corundum of varying qualities occurring in association with Khammam schist belt are studied with respect to their Geochemical and Mineralogical aspects. Studies have been carried out using the advanced spectroscopic tech...