Microencapsulation by spray drying of Lannea microcarpa extract: Technological characteristics and antioxidant activity
Journal Title: Journal of Pharmacy & Pharmacognosy Research - Year 2014, Vol 2, Issue 4
Abstract
Context: A functional extract from Lannea microcarpa (Lm), possess interesting antioxidant and anti-inflammatory properties. However, the unprocessed dried extract occurs as sticky and low-water-soluble material showing critical properties for industrial applications. The unprocessed dried extract is not always enough stable to preserve its functional properties, also giving practical difficulties for the manufacturing. Aims: This research aimed to produce Lm extract microparticles with enhanced functional stability and technological characteristics by spray-drying. Methods: Lm extract was microencapsulated by spray-drying using a sodium-carboxymethylcellulose (NaCMC) based matrix. Physicochemical and technological characteristics (determined by UV, HPLC, LLS, SEM, DSC, and in vitro dissolution tests), as well as antioxidant properties (DPPH-test) of the resulting powder (LmC) were examined. Results: The produced spray dried microparticles showed satisfying encapsulation efficiency, good functional stability and enhanced technological properties. The selected carrier and process conditions led to a stable and handling microencapsulated powder form with improved water dissolution rate. Moreover, the matrix was also able to preserve the antioxidant activity of the phenolic compounds-rich extract. Conclusions: The made-up powder resulted in a functional component that can be used with great potential in cosmetics, foods or nutraceutical products.
Anti-inflammatory activity of the methanolic extracts of leaves and stems from Tabebuia hypoleuca (C. Wright) Urb.]
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Esta tesis está vinculada con el área de la farmacognosia y el estrés oxidativo. Los conocimientos sobre los aceites presentes en las semillas de diferentes frutos sirvieron de base para que en el Laboratorio de Product...
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Negative inotropic and dromotropic actions of SiO2 nanoparticles on isolated rat hearts: Effects on Na+ and Ca2+ currents
Context: SiO2 nanoparticles (NP) are widely used in the industry and in varied biotechnological and medical applications. However, epidemiological studies suggest that pollution with fine particles (in which silica is an...