Mirena and NuvaRing in Management in Dysfunctional Uterine Bleeding
Journal Title: International Journal of Contemporary Medical Research - Year 2018, Vol 5, Issue 4
Abstract
Introduction: Abnormal uterine bleeding in reproductive age group is one of the commonest gynecological problems in women. Ovulatory dysfunction is one of the commonest causes of AUB. Combined oral contraceptive pills and oral progesterone are used as first line treatment of ovulatory dysfunction. However many women may not be desirous of oral medication. In such circumstances keeping in view of patient preferences and her medical condition, vaginal rings and intrauterine devices containing hormonal preparations may be a preferable. Material and Methods: Two groups including 80 women in each group who were fulfilling the inclusion criteria were selected. In one group NuvaRing which releases 15μg ethinyl estradiol and 120μg etonogesterol daily and requires intravaginal monthly insertion and in the other group of patients Mirena which is a intrauterine device with levonogestrol was inserted. Both groups were followed up for 4 months. The efficacy and side effects were measured in terms of change menstrual cycle pattern and Primary Outcome Pictorial Blood Loss Assessment chart (PBAC) score. Other parameters included side effects and acceptability of the device used. Data was analyzed by statistical software SPSS 21.0. Results: NuvaRing and Mirena were offered to women in reproductive age group for management of dysfunctional uterine bleeding which resulted in significant symptomatic improvement, and a statistically significant decline in PBAC score. These women also had an increase in hemoglobin levels and improved feeling of wellbeing. Conclusion: Both NuvaRing and Mirena can be used for management of abnormal uterine bleeding. The initial response to symptomatic improvement in terms of PBAC score was better with NuvaRing but in the final outcome both are comparable.
Authors and Affiliations
Shalini Vasudeva1, Gunjan Malhotra, SK Gulati, YS Chandel
Keywords
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