Mitomycin C combined with anterograde lacrimal drainage tube implantation for the treatment of upper lacrimal duct obstruction

Journal Title: Guoji Yanke Zazhi - Year 2018, Vol 18, Issue 12

Abstract

AIM: To explore the application effect of mitomycin C in lacrimal duct obstruction during anterograde lacrimal drainage tube implantation. <p>METHODS:Totally 78 cases of lacrimal duct obstruction(82 eyes)were randomly divided into the observation group(39 cases, 42 eyes)and the control group(39 cases, 40 eyes), and the control group was treated with lacrimal drainage tube implantation. The observation group was based on this combined mitomycin C treatment and compared the effect of two groups. <p>RESULTS: The total effective rate of the observation group was 81%, which was significantly higher than that of the control group(62%), and the difference between the two groups was statistically significant(<i>P</i><0.05). The eye surface change score(26.25±1.67)and tear SP content(256.32±10.07pg/mL)were lower than that of the control group after treatment. The tear film rupture time(8.85±0.89s)was shorter than that of the control group(9.58±0.92s), and the two groups were statistically significant(<i>P</i><0.05). <p>CONCLUSION: Mitomycin C can improve the efficacy of anterograde lacrimal drainage tube implantation for the treatment of lacrimal duct obstruction and improve prognosis.

Authors and Affiliations

Xin Qian

Keywords

Related Articles

Study of wavefront aberration in DR patients with different degree of dry eye

AIM: To compare the changes of wavefront aberrations in patients with diabetic retinopathy(DR)and with different degrees of dry eye and to explore the reasons of visual quality decline in them. <p>METHODS: We randomly se...

Diagnosis and management of familial exudative vitreoretinopathy

Familial exudative vitreoretinopathy(FEVR)is a rare inherited disorder of retinal angiogenesis. It is characterized by avascular peripheral retina. Mutations in FZD4, NDP, LRP5, TSPAN12, ZNF408, KIF11 have been found the...

Clinical study of SMILE on the correction of large astigmatism for 2a

AIM: To observe the surgical results of large astigmatism with small incision lenticule extraction(SMILE)for 2a. <p>METHODS: Totally 33 eyes of 17 consecutive patients were enrolled in this retrospective study, aged from...

Significance of ocular surface interferometer in the diagnosis of Meibomian gland dysfunction

AIM: To investigate the significance of ocular surface interferometer in the diagnosis of Meibomian gland dysfunction(MGD).<p>METHODS: Prospective case-control studies. Totally 62 patients with MGD and 38 healthy volunte...

Mechanism of TUDCA for retinitis pigmentosa

Tauroursodeoxycholic acid(TUDCA)is formed by taurine conjugated of ursodeoxycholic acid(UDCA). It has the role of neurotrophic factor in anti-inflammatory, anti-apoptosis and reducing the activation of microglial cells....

Download PDF file
  • EP ID EP501807
  • DOI 10.3980/j.issn.1672-5123.2018.12.38
  • Views 126
  • Downloads 0

How To Cite

Xin Qian (2018). Mitomycin C combined with anterograde lacrimal drainage tube implantation for the treatment of upper lacrimal duct obstruction. Guoji Yanke Zazhi, 18(12), -. https://europub.co.uk./articles/-A-501807