Modified method for partial purification of human blood clotting factor VIII from fresh frozen plasma
Journal Title: Medpulse International Journal of Biochemistry - Year 2017, Vol 3, Issue 3
Abstract
Human blood is an irreplaceable commodity. Its proteinaceous structure, the compatibility and others. Factor VIII to the haemophilic patient provides need to make available Clotting Factor VIII from freeze dried fresh plasma with Factor VIII of coagulation has longer shelf life (2 years) and can be introduced to the patient with less interference of immunological complications. The present study established cryoprecipitate - rich in Coagulation Factor VIII without significant loss of activity. The gradual treatment of change in temperature followed by lyophilisation produced enriched fraction. Thus the Coagulation Factor for infusion to the required haemophilic patient readily.
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