MOLECULAR COMPLEXES OF GERMANIUM TETRACHLORIDE WITH NIACIN, NICOTINIC AMIDE, ISONICOTINIC HYDRAZIDE AND THEIR PHARMACOLOGICAL ACTIONS
Journal Title: Вісник Одеського національного університету. Хімія - Year 2016, Vol 21, Issue 2
Abstract
Synthesized in different organic solvents and characterized by elemental and X-ray diffraction, thermogravimetry, IR spectroscopy molecular complexes of germanium tetrachloride with niacin, nicotinic amide and isonicotinic hydrazide. Determined that in obtained compounds the coordination of the ligand is due to the unshared electron pair on the nitrogen atom of the heterocycle. Proposed structure of the complexes. Showed their high antihypoxic, hepatoprotective, antioxidant and membrane-stabilizing activity of the synthesized compounds.
Authors and Affiliations
I. I. Seifullina, E. E. Martsinko, N. M. Khristova, E. A. Chebanenko
Keywords
Related Articles
- EP ID EP337054
- DOI 10.18524/2304-0947.2016.2(58).74777
- Views 82
- Downloads 0
SYNTHESIS AND HEMOLYTIC PROPERTIES OF DERIVATIVES OF 4,4'-DIHYDROXYBIPHENYL – 2,2'-[BIPHENYL-4,4'- DIYLBIS(OXY)]BIS[N-(METHYLAMINO)ALKILACETAMIDES]
The purpose of this work was synthesis of 4,4’-dihydroxybiphenyl derivatives, namely 2,2’-[biphenyl-4,4’-diylbis(oxy)]bis[N-(2-aminoalkyl)acetamide], study of their hemolytic properties and the effect of the side chain s...
RECONSTRUCTION OF CALCINED Zn -Al LAYERED DOUBLE HYDROXIDES DURING TETRACYCLINE ADSORPSION
Zn-Al mixed oxides containing ZnO different degree crystallinity were obtained by calcinations of Zn-Al layered double hydroxides (LDHs). The reconstruction of calcined Zn-Al LDHs has been performed under stirring in aqu...
SPECTROSCOPIC STUDIES OF COMPLEX COMPOUNDS OF COBALT(III) -NICKEL(II) WITH DIETANOLAMINE
Polynuclear complex compounds of 3d metals with amino alcoholic ligands can be used to obtain effective electrocatalysts for the process of lithium intercalation in graphite from organic aprotic electrolytes, occurring i...
THIN EMULSIFIED SOLUTIONS OF TRIALKYLAMINE IN KEROSENE AS COLLECTORS FOR FLOTATION–EXTRACTION OF THORIUM (VI) COMPOUNDS
The principle possibility of using the thin emulsified solutions of trialkylamine in kerosene as collector of thorium compounds for their flotation extraction has been established. The colloid- chemical properties of the...
THE ACID-BASE AND CHROMATICITY CHARACTE RISTICS OF FOOD DYE «SUNSET YELLOW FCF»
The acid-base properties of yellow food dye E110 «Sunset Yellow FCF» was studied by chemical chromaticity, spectrophotometric and potentiometric methods in aqueous solutions and identified relevant ionization constants....