MONSTER PHASE OF ACETAMINOPHEN USE IN PREGNANCY: CURRENT VISION OF AN OLD DRUG
Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2016, Vol 8, Issue 11
Abstract
In various countries, Acetaminophen [APAP] is the frequently used painkiller found in hundreds of medications during pregnancy. It has been broadly used for eras and health care professionals prefer acetaminophen as a choice during pregnancy for relieving pain and fever. Current research reports bothersome inclinations in the rate of acetaminophen exposure and related pregnancy outcome. The exposure of pregnant women to acetaminophen is of great concern. Existing literature evidence shows that acetaminophen exposure during pregnancy may leads to preterm birth, attention deficit hyperactivity disorder (ADHD), autism, male infertility, asthma in pediatrics. Therefore, the prophylactic anticipation of acetaminophen exposure can be a far-sighted approach in order to safeguard humans and wildlife from enduring dangerous effects. This article reviews the epidemiological findings and aims to shed awareness into the second generation outcome of an old drug in pregnant women.
Authors and Affiliations
Nisha Rani S. s. , Gomathi Swaminathan, Sambathkumar R.
MOLECULAR DOCKING STUDY OF FLAVONOID COMPOUNDS AS INHIBITORS OF Î’-KETOACYL ACYL CARRIER PROTEINSYNTHASE II (KAS II) OF PSEUDOMONAS AERUGINOSA
Objective: Fatty acid biosynthesis is essential for bacterial survival. Components of this biosynthetic pathway have been identified as attractive targets for the development of new antibacterial agents. β–Ketoacyl ac...
SILVER NANOPARTICLES SYNTHESIS FROM DIFFERENT FUNGAL SPECIES AND THEIR ANTIFUNGAL EFFECT
Objective: Evaluation of antifungal activity of silver nanoparticles synthesized using different fungal speciesMethods: Fungus like Fusarium oxysporum, Fusarium udum, Fusarium oxysporum and Stemphylium vericans were used...
SOLID LIPID NANOPARTICLES AND NANOSTRUCTURED LIPID CARRIERS OF TOLNAFTATE: DESIGN, OPTIMIZATION AND IN-VITRO EVALUATION
Objective: The target of our work is the preparation of tolnaftate (TOL) loaded solid lipid nanoparticles (SLNs) as well as nanostructured lipid carriers (NLCs).Methods: The high shear homogenization method was chosen fo...
EFFECTS OF CIPROFLOXACIN IN COMBINATION WITH EITHER AMINOGUANIDINE OR MECLOFENAMIC ACID IN MODULATING S. AUREUS INDUCED SEPTIC ARTHRITIS IN MICE
Objective: Staphylococcus aureus (S. aureus) is a potent causative organism of septic arthritis. In this study, ciprofloxacin was used to nullify the bacterial burden in mice infected with pathogenic strain of S. aureus....
IN SILICO MOLECULAR DOCKING OF XANTHONE DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITOR AGENTS
Objective: To demonstrate the potential ofdifferent xanthone derivatives as cyclooxygenase-2 (COX-2) inhibitor agents and their selectivity against cycloooxygenase-1 (COX-1) and COX-2 using molecular simulation.Methods:...