MORPHOLOGICAL STUDY OF SYNOVIAL LESIONS IN CHRONIC JOINT DISEASE
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 27
Abstract
BACKGROUND Joint disease is a common problem, which affects all age groups. Delay in proper diagnosis may lead to inability to control the disease process, leading to irreversible damage to the joints. Synovial biopsy is an important investigation, which is a useful adjunct to confirm the diagnosis. The objective of this study is to describe the morphological features of synovial biopsy specimens in various joint diseases. MATERIALS AND METHODS A descriptive study was conducted on 77 cases of synovial biopsy specimens received in the Department of Pathology, Government Medical College, Kottayam during a period of 18 months (May 2016 - November 2017). RESULTS Among 77 cases, 67 were monoarticular and 10 were polyarticular. Knee joint was the most commonly involved joint in 48 cases (62.3%) followed by hip and ankle joint in 7 cases each (9.1% each). Infectious arthritis (septic arthritis) with chronic joint disease was the most common lesion diagnosed (42%) followed by Osteoarthritis (OA) (14%), Tubercular arthritis (TBA) (12%) and Rheumatoid arthritis (RA) (10%). Synovial fluid was analysed in 31 cases. Among that 25 cases were infectious arthritis, 3 cases were OA, 1 case was RA, 1 case was TBA and 1 case was Gouty arthritis (GA). Radiological diagnosis by x-ray has got the highest sensitivity (100%) in diagnosing Giant cell tumour (GCT), Charcot joint and GA followed by OA (90.9%). CONCLUSION Infectious arthritis with chronic joint disease was the most common lesion diagnosed (42%) followed by osteoarthritis (14%), TBA (12%) and RA (10%). Synovial biopsy may give conclusive diagnosis where clinical diagnosis is equivocal.
Authors and Affiliations
Abinaya Devi A, Lekshmi Devi P, Sankar S
Keywords
Related Articles
- EP ID EP467169
- DOI 10.14260/jemds/2018/701
- Views 93
- Downloads 0
THE PATTERN OF BACTERIAL PATHOGENS AND THEIR ANTIBIOTIC SUSCEPTIBILITY PROFILE FROM LOWER RESPIRATORY TRACT SPECIMENS IN A RURAL TERTIARY CARE CENTRE
BACKGROUND Lower Respiratory Tract Infections (LRTIs) is one of the leading infective health problems worldwide. The inappropriate use of antibiotics for these infections has led to a dramatic increase in antibi...
A CLINICAL, BACTERIOLOGICAL AND LABORATORIES PROFILE OF NEONATAL SEPTICAEMIA IN A TERTIARY CARE CENTRE OF EASTERN NEPAL
BACKGROUND The most common neonatal morbidity and mortality in underdeveloped countries is neonatal sepsis. The vague clinical sign and symptoms need high degree of suspicion for the early diagnosis and treatment, while...
PREVALENCE OF ALLERGIC FUNGAL SINUSITIS
Allergic fungal sinusitis (AFS) is a disease of young immune competent adults. Nasal obstruction, nasal discharge, nasal allergy and proptosis were the most common presentations. Initial diagnosis of allergic...
A STUDY OF ASSOCIATION OF SEX HORMONES WITH INSULIN RESISTANCE AND OBESITY FOR DIABETES MELLITUS RISK IN ADULT WOMEN
BACKGROUND Sex hormones have a great impact on energy metabolism, body composition, vascular function and inflammatory responses and insulin resistance. Ovarian hormones influence insulin sensitivity across the lifespan...
SENSORY NERVE CONDUCTION VELOCITY IN SUBJECTS WITH IRON-DEFICIENCY ANAEMIA
BACKGROUND The predominant cause of anaemia in the general population is iron-deficiency anaemia, but there are little data about the peripheral nerve sensory function in subjects with iron-deficiency anaemia....