MORPHOLOGICAL STUDY OF SYNOVIAL LESIONS IN CHRONIC JOINT DISEASE
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 27
Abstract
BACKGROUND Joint disease is a common problem, which affects all age groups. Delay in proper diagnosis may lead to inability to control the disease process, leading to irreversible damage to the joints. Synovial biopsy is an important investigation, which is a useful adjunct to confirm the diagnosis. The objective of this study is to describe the morphological features of synovial biopsy specimens in various joint diseases. MATERIALS AND METHODS A descriptive study was conducted on 77 cases of synovial biopsy specimens received in the Department of Pathology, Government Medical College, Kottayam during a period of 18 months (May 2016 - November 2017). RESULTS Among 77 cases, 67 were monoarticular and 10 were polyarticular. Knee joint was the most commonly involved joint in 48 cases (62.3%) followed by hip and ankle joint in 7 cases each (9.1% each). Infectious arthritis (septic arthritis) with chronic joint disease was the most common lesion diagnosed (42%) followed by Osteoarthritis (OA) (14%), Tubercular arthritis (TBA) (12%) and Rheumatoid arthritis (RA) (10%). Synovial fluid was analysed in 31 cases. Among that 25 cases were infectious arthritis, 3 cases were OA, 1 case was RA, 1 case was TBA and 1 case was Gouty arthritis (GA). Radiological diagnosis by x-ray has got the highest sensitivity (100%) in diagnosing Giant cell tumour (GCT), Charcot joint and GA followed by OA (90.9%). CONCLUSION Infectious arthritis with chronic joint disease was the most common lesion diagnosed (42%) followed by osteoarthritis (14%), TBA (12%) and RA (10%). Synovial biopsy may give conclusive diagnosis where clinical diagnosis is equivocal.
Authors and Affiliations
Abinaya Devi A, Lekshmi Devi P, Sankar S
Keywords
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- EP ID EP467169
- DOI 10.14260/jemds/2018/701
- Views 87
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