Morphology Of Cultured Cells Of Glioblastoma Multiforme
Journal Title: Journal of Neurological Sciences-Turkish - Year 2007, Vol 24, Issue 2
Abstract
The aim of the present study is to asses the morphology of cultured glioblastoma multiforme cells obtained from five patients. Established tissue cultures of malignant astrocytoma cells showed polymorphic characters phenotypically. There were various types of tumor cells including ovoid cytoplasm with multiple processes, elongated unipolar and bipolar, spindle, bizarre in shape, and large flat cell as well as multinucleated gigantic form. As the passage of the tissue culture of glioblastoma multiforme continued, their cell morphology became more similar in appearance. In the present study, the glioblastoma multiforme cells in vitro included heterogeneous subpopulations of tumor cells, which may explain why the treatment modalities remain insufficient in clinics.
Authors and Affiliations
Ramazan DURMAZ
Keywords
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