MORPHOMETRIC STUDY OF THIRD VENTRICLE WIDTH IN NORTH INDIAN POPULATION: A CT STUDY
Journal Title: JOURNAL OF ANATOMICAL SCIENCES - Year 2017, Vol 25, Issue 1
Abstract
Introduction: Brain is one of the most complex and magnificent organs in the human body. Ventricular system of brain comprises of two lateral ventricles, third ventricle and a fourth ventricle. As brain ages, there is a decrease in size of brain tissue accompanied by ventricular system enlargement along with increased cerebrospinal fluid volume. Ventricular enlargement also takes place in hydrocephalus and neurodegenerative conditions like Huntington’s disease. It is very important to distinguish the pathological ventricular enlargement from age related ventricular enlargement. Keeping this in mind we endeavored to contribute a database for normal width of third ventricle in North Indian population. Material and methods: A prospective study was conducted, whereby, radiologically normal CT scans of head region, belonging to 100 patients were subjected to thorough analysis in Radiant DICOM Viewer Software. The study was a joint venture between the Department of Anatomy and Department of Radiodiagnosis, King George’s Medical University, Lucknow. The width of third ventricle taken at the level of interventricular foramen was measured on axial scans as the maximum distance between the two thalami. The study involved 51 males and 49 females (n=100) normal subjects ranging from 18 to 76 years, that were grouped into different categories according to age; 18-30 years, 31-40 years, 41-50 years, 51-60 years and above 60 years. Results: Width of third ventricle was found ranging from 0 mm (trace/not measurable) to 8.4 mm with a mean of 3.62 mm and displayed a significant increase with increasing age. It was wider in males (3.92±2.42 mm) than females (3.30±1.72 mm). Width was found to be minimal and difficult to visualize in persons aged less than 35 years. Conclusion: Knowledge about the mean width in different age groups and in either gender may help in diagnosis of some neurological disorders below the age of 49 years.
Authors and Affiliations
Garima Sehgal
Keywords
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