Mortality predictors in acute exacerbation of COPD: A prospective study in Western India
Journal Title: IP Indian Journal of Immunology and Respiratory Medicine - Year 2018, Vol 3, Issue 3
Abstract
Introduction Chronic Obstructive Pulmonary Disease COPD is a leading cause of morbidity and mortality worldwide In 2016 COPD was the third leading cause of death Thus prevention early detection and prompt treatment of exacerbations may have an impact on the clinical progression and the risk of hospitalizationMaterial and Methods This is a prospective study of 94 patients admitted for acute exacerbation of COPD in a tertiary care hospital over a period of 18 months After a detailed medical history and physical examination patients blood was sent for Arterial Blood Gas ABG analysis a complete hemogram blood sugar levels serum albumin levels blood urea nitrogen levels BUN serum creatinine levels SGPT SGOT serum sodium and potassium levels We have then compared these parameters in the patients who have died with those who have survived to determine mortality predictorsResult A statistically significant corelation was observed between male gender smoking odd ratio of 15 duration of smoking p00014 history of prior admission odd ratio of 2 longer duration of illness p0045 elevated blood sugar levels p0035 hypolabuminemia 0001 hypopnatremia 0001 respiratory acidosis 0003 elevated partial pressure of CO2 0001 and mortalityConclusion We found a male preponderance of increased mortality Increase in mortality was also there with the increase in the duration of smoking Longer duration of illness was also an important predictor of mortality Respiratory acidosis hyponatremia elevated blood sugar levels and hypoalbuminemia at the time of presentation are other important predictors of mortality in patients hospitalized for acute exacerbation of COPDKeywordsAcute exacerbation Chronic obstructive pulmonary disease COPD Predictors Mortality
Authors and Affiliations
Rushi R. Patel, Dharmeshkumar S Patel
Keywords
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- EP ID EP490600
- DOI 10.18231/2581-4222.2018.0028
- Views 81
- Downloads 0
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