Multicentric study on the efficacy and tolerability of Streptococcus salivarius 24SMB and Streptococcus oralis 89a in respiratory tract infections
Journal Title: Romanian Journal of Rhinology - Year 2018, Vol 8, Issue 29
Abstract
BACKGROUND. Bacteriocins are peptides with antimicrobial efficacy produced by certain bacterial species. Probiotics indeed seem a promising method in the prevention of upper respiratory infections and our study would like to contribute to the results available in the literature, in order to underlie their true therapeutic potential role. MATERIAL AND METHODS. Our multicenter pilot prospective study investigates 366 patients from September 2015 to February 2016. All the patients were treated with a topical device made up of a suspension of two specific bacterial strains: Streptococcus salivarius 24SMB and Streptococcus oralis 89a to be administered as nasal spray. The nasal spray was administered twice daily for 7 days per month for three consecutive months. A questionnaire about the subjective efficacy of the therapy correlated to an improvement of symptoms was also collected from patients. RESULTS. After one year from the enrolment, a 70.07% reduction in the number of events compared with the number of expected episodes was observed. CONCLUSION. The aim of our data is to propose a new therapeutic approach to treat the recurrence of upper airway infection and to support an adequate therapy in all cases where the traditional antibiotic therapeutic protocol did not obtain completely efficient results in terms of recurrence.
Authors and Affiliations
Luisa Maria Bellussi, Desiderio Passali, Emanuela Vesperini, Serena Cocca, Giulio Cesare Passali, Roberto Albera, Domenico Rosario Cuda, Michele De Benedetto, Gaetano Motta, Giuseppe Panetti, Marco Piemonte, Lorenzo Salerni, Felice Scasso, Giancarlo Vesperini
Keywords
Related Articles
- EP ID EP265867
- DOI 10.2478/rjr-2018-0004
- Views 104
- Downloads 0
Multicentric study on the efficacy and tolerability of Streptococcus salivarius 24SMB and Streptococcus oralis 89a in respiratory tract infections
BACKGROUND. Bacteriocins are peptides with antimicrobial efficacy produced by certain bacterial species. Probiotics indeed seem a promising method in the prevention of upper respiratory infections and our study would lik...
Comparison of microdebrider-assisted endoscopic sinus surgery and conventional endoscopic sinus surgery for chronic rhinosinusitis with nasal polyps
OBJECTIVE. To study and compare the benefits of microdebrider-assisted endoscopic sinus surgery and conventional endoscopic sinus surgery in terms of subjective and objective improvement in symptoms of nasal polyposis. M...
Computed-tomography volumetric study of the ethmoid labyrinth
Morphological variability of paranasal sinuses is well known for endoscopic surgeons and anatomists alike. The ethmoid sinus is the most complex and variable of all paranasal sinuses, due to the fact that its development...
Sinonasal adenocarcinoma with aggressive ocular symptom
BACKGROUND. The malignant sinonasal tumour is very rare. Sinonasal adenocarcinoma comprises only 10-20% of all primary malignant sinonasal tumours. The commonest type is the maxillary squamous cell carcinoma. It commonly...
European standards and North American practice parameters for skin prick testing panels in allergic rhinitis and asthma
According to the Global Allergy and Asthma European Network (GA²LEN), a pan-European skin prick test panel for the diagnosis of allergic rhinitis and asthma includes 18 aeroallergen extracts, supplemented if necessary fo...