Multidetector Computed Tomography Evaluation of Subtypes of Renal Cell Carcinoma
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2017, Vol 5, Issue 5
Abstract
Introduction: Renal cell carcinoma (RCC) accounts for approximately 5% of all cancers in men and 3% in women and is the second most common urologic neoplasm.1 Aim: The purpose of our study is to identify the different demographic characteristics of patients with RCC, to study different features of subtypes on multidetector computed tomography (MDCT), and to determine the differentiating features of subtypes. Materials and Methods: We reviewed four subtypes of RCC. 24 patients with RCC who underwent nephrectomy, pre-operative MDCT evaluation, and with pathological diagnosis of RCC were included in our study. Features of tumors and attenuation pattern in CT were evaluated and analyzed. Results: The clear cell RCC was the most common (75%) tumor subtype with smaller size of the lesion at presentation, heterogeneous enhancement, and cystic degeneration, hypervascularity with post-contrast HU of >100 in corticomedullary phase. The tumor had various patterns of spread and the tumor to aorta enhancement ratio was >0.3. The papillary RCC (pRCC) was 17%, smaller lesions, and hypovascular with post-contrast HU of <100. The tumor-to-aorta enhancement ratio was <0.23. Single case of translocation type RCC (4%) and chromophobe RCC (4%) were observed which presented with intermediate features and tumor-to-aorta enhancement ratio was 0.3 and 0.23-0.3, respectively. Chromophobe RCC showed calcification and high-attenuation values. Excepting pRCC, other subtypes were observed more in females. Conclusion: In addition to CT tumor attenuation values, the combination of other parameters play an important role in diagnosing and differentiating among the different subtypes of RCC. Other important differentiating parameter observed was tumor-to-aorta enhancement ratio.
Authors and Affiliations
A Rohini, Vidya Bhargavi, Prachi Kala
Keywords
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