Multidetector Computed Tomography Evaluation of Subtypes of Renal Cell Carcinoma
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2017, Vol 5, Issue 5
Abstract
Introduction: Renal cell carcinoma (RCC) accounts for approximately 5% of all cancers in men and 3% in women and is the second most common urologic neoplasm.1 Aim: The purpose of our study is to identify the different demographic characteristics of patients with RCC, to study different features of subtypes on multidetector computed tomography (MDCT), and to determine the differentiating features of subtypes. Materials and Methods: We reviewed four subtypes of RCC. 24 patients with RCC who underwent nephrectomy, pre-operative MDCT evaluation, and with pathological diagnosis of RCC were included in our study. Features of tumors and attenuation pattern in CT were evaluated and analyzed. Results: The clear cell RCC was the most common (75%) tumor subtype with smaller size of the lesion at presentation, heterogeneous enhancement, and cystic degeneration, hypervascularity with post-contrast HU of >100 in corticomedullary phase. The tumor had various patterns of spread and the tumor to aorta enhancement ratio was >0.3. The papillary RCC (pRCC) was 17%, smaller lesions, and hypovascular with post-contrast HU of <100. The tumor-to-aorta enhancement ratio was <0.23. Single case of translocation type RCC (4%) and chromophobe RCC (4%) were observed which presented with intermediate features and tumor-to-aorta enhancement ratio was 0.3 and 0.23-0.3, respectively. Chromophobe RCC showed calcification and high-attenuation values. Excepting pRCC, other subtypes were observed more in females. Conclusion: In addition to CT tumor attenuation values, the combination of other parameters play an important role in diagnosing and differentiating among the different subtypes of RCC. Other important differentiating parameter observed was tumor-to-aorta enhancement ratio.
Authors and Affiliations
A Rohini, Vidya Bhargavi, Prachi Kala
Keywords
Related Articles
- EP ID EP471189
- DOI -
- Views 101
- Downloads 0
Comparative Study of Akin Staging and Pediatric - Risk, Injury, Failure, Loss, End-stage Kidney Classification in Identifying Acute Kidney Injury in Critically Ill Children
Introduction: Acute kidney injury (AKI) is a common comorbidity in critically ill children, associated with an increased risk of morbidity and mortality. Modern definitions of AKI based on changes in serum creatinine (Cr...
A Comparative Study of Pulmonary Function Tests between Normal Male Sedentary and Tennis Players
Background: In the assessment of the respiratory system, pulmonary function tests (PFTs) have achieved a lot of importance nowadays due to an increase in the cardiorespiratory disease and to a steep rise in air pollution...
Randomized Comparative Study of Drug Regimens: Fentanyl with Propofol and Fentanyl with Midazolam as Sedating Agents in Day Care Oral Surgery
Introduction: Widespread use of general anesthesia is limited by the risk associated, requirement of adequate equipment, extensive training required, and the cost. The use of intravenous agents in conjunction with local...
Audiological Evaluation of Children below 14 Years Undergoing Tympanoplasty in a Tertiary Teaching Hospital
Introduction: Chronic suppurative otitis media (CSOM) is at a higher incidence in the pediatric population when compared to adults. CSOM results in conductive deafness resulting in difficulty in learning speech skills. S...
Role of Health Care Workers During Emergency Preparedness in Selected Hospitals of Navi Mumbai
Introduction: Health services being the most crucial service from the point of view of caring and rehabilitation of injured patients. Medical Facilities for patients care, requires the highest state of preparedness aroun...