MULTIPLE PRIMARY MALIGNANT NEOPLASMS- AN INTERESTING CASE REPORT
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 39
Abstract
PRESENTATION OF CASE A 65-year-old male with complaints of lump in left breast since 2 years. CT scan findings were non-homogeneous mass in left breast along with bilateral axillary lymphadenopathy. Lumpectomy was performed and diagnosed as infiltrating duct carcinoma breast. After that, we received modified radical mastectomy specimen in our lab. On gross examination, subareolar cavity was surrounded by whitish solid area of 2 cm without involvement of skin. Total 26 lymph nodes were retrieved. Lymph nodes were whitish and fleshy {Fig. 1}. The resection specimen was fixed in formalin, routinely processed and multiple representatives of 3-micron sections were stained with haematoxylin and eosin stain and Immunohistochemistry (IHC) was also performed. Microscopic examination showed the features of infiltrating duct carcinoma NOS: Modified Nottingham Bloom Richardson’s Grade II in breast specimen. All the lymph nodes were submitted for processing and H and E stained sections taken from all the submitted lymph nodes showed the complete effacement of lymph node by small lymphocytes having slightly irregular round nuclei. The chromatin was condensed, and cytoplasm was scanty [Fig. 3]. None of the lymph nodes showed any metastatic deposits. Peripheral smear of patient showed features of chronic lymphocytic leukaemia (absolute lymphocyte count was 16400 cells/mm3) [Fig. 5].
Authors and Affiliations
Chandni Krishnani, R. K. Tandon, S. S. Goswami, Payal Desai
Keywords
Related Articles
- EP ID EP548170
- DOI 10.14260/jemds/2018/962
- Views 63
- Downloads 0
FNAC OF HIV LYMPHADENOPATHY IN A TERTIARY CARE HOSPITAL: A TWO YEAR STUDY
The incidence of Human Immunodeficiency Virus (HIV) infection is seen to be increasing in Asia, particularly in the Indian subcontinent. Immune system and the central nervous system are the two major targets of...
AMYLOID GOITRE: A RARE CASE STUDY
Involvement of the thyroid gland by amyloidosis is a common phenomenon but clinically significant enlargement of the thyroid owing to amyloid deposition is an extremely rare occurrence. Amyloid Goitre is defined as a...
EFFECT OF BODY MASS INDEX ON BLOOD PRESSURE AND LIPID PROFILE
BACKGROUND The importance of maintaining a healthy BMI is known all over the globe. Obesity causes Heart diseases, increase the potential for Type 2 Diabetes Mellitus, increased risk of Stroke, Carcinomas, Hypertension a...
WRIST HAND ORTHOSES IN THE MANAGEMENT OF UPPER LIMB SPASTICITY IN HEMIPLEGIA- A RANDOMISED CONTROLLED TRIAL STUDY
BACKGROUND The most significant impact on a stroke survivor is longterm disability. Patients with hemiplegia often develop abnormal patterns in the paretic limbs, primarily affecting the flexors and pronators of upper li...
STUDY ON PREGNANCY OUTCOME IN PRETERM PREMATURE RUPTURE OF MEMBRANES WITH OLIGOHYDRAMNIOS
BACKGROUND Pregnancy outcome in preterm premature rupture of membranes is affected by AFI. PPROM with oligohydramnios (AFI<5) affects maternal outcome in terms of latency period, complications like chorioamnionitis, mode...