Mycobacterium Tuberculosis
Journal Title: International Journal of Biomedical and Advance Research - Year 2016, Vol 7, Issue 5
Abstract
Tuberculosis (TB) is a potentially fatal contagious disease that can affect almost any part of the body but is mainly an infection of the lungs. It is caused by a bacterial microorganism, the tubercle bacillus or Mycobacterium tuberculosis. Although TB can be treated, cured, and can be prevented if persons at risk take certain drugs, scientists have never come close to wiping it out. Diagnosis still depends largely on sputum microscopy, which is unsuitable for a large number of patients. The efficacy of the BCG vaccine is limited. Major obstacle in the cure and prevention of tuberculosis is posed by the latent or persistent M. tuberculosis infection. This is due to the fact that most of the currently available drugs are ineffective against latent infection. Scientist are searching for new targets for mycobacterium tuberculosis disease through biological studies (Proteonomics, Bioinformatics) then Synthetic modification in existing drug & study of some naturally existing drug. This review is useful to study the disease tuberculosis, Bacillus Characteristics, Clinical aspect, drug resistance study, treatment and study of new drug target for mycobacterium tuberculosis.
Authors and Affiliations
S. C. Kale, M. K. Kale, Sarita Singhal
Keywords
Related Articles
- EP ID EP364309
- DOI 10.7439/ijbar.v7i5.3193
- Views 85
- Downloads 0
A Study Of Variations In The Origin Of Vertebral Artery And Its Clinical Significance
Objectives: An understanding of anatomy is essential to surgeons and knowledge of variations is of practical importance. The anatomic and morphologic variations of great vessels are significant for diagnostic and surgica...
Health concerns of migrants and refugees
Migration is a process of social change during which a person moves from one cultural setting to another in order to settle for a longer period of time or permanently. If internal and international migrants are being tak...
The study of risk factors associated with dyspepsia
Dyspepsia is defined as upper abdominal or retrosternal pain or discomfort referable to theproximal alimentary tract. Dyspepsia is a major health problem. The aim of the study is to find out the risk factors associated w...
Hypothyroidism and possible association with Metabolic Syndrome
Background: Thyroid dysfunctions are the most common forms of endocrine disorder in our country, Thyroid hormones perform a wide array of metabolic functions including regulation of lipids, carbohydrates, protein and ele...
Post Coronary Artery Bypass Grafting Coronary Artery Spasm: A Case Report
Coronary artery spasm after coronary artery bypass grafting (CABG) is a rarephenomenon often resulting in heart failure. We report a case of 56-yearr-old male, who had coronary artery spasm after CABG, which was successf...