Nanogel as a Pharmaceutical Carrier – Review Article
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2017, Vol 5, Issue 11
Abstract
Abstract: A nanoparticle which is composed of a hydrogel with a cross linked hydrophilic polymer network is known as “Nanogel”. The term ‘nanogels’ defined as the nanosized particles formed by physically or chemically cross-linked polymer networks that is swell in a good solvent. The term “nanogel” was first introduced to define cross-linked bifunctional networks of a polyion and a nonionic polymer for delivery of polynucleotides (cross-linked polyethyleneimine (PEI) and poly (ethylene glycol) (PEG) or PEG-cl-PEI). Sudden outbreak in the field of nanotechnology have introduced the need for developing nanogel systems which proven their potential to deliver drugs in controlled, sustained and targetable manner. With the emerging field of polymer sciences it has now become inevitable to prepare smart nano-systems which can prove effective for treatment as well as clinical trials progress. The brief review aims at providing comprehensive illustrations on the novel applications, drug loading technique, mechanism of drug release from nanogels. Further, current status, clinical trial status, and future perspective of nanogels have been summarized. Keywords:Nanoparticle, Nanogel, Nanotechnology, polymer.
Authors and Affiliations
Fateh AL Rahman, Magbool F, Elamin Ibrahim Elnima, Shayoub M E, Salah Eldin Omar Hussein
Keywords
Related Articles
- EP ID EP372674
- DOI -
- Views 59
- Downloads 0
Comparative Study of Asymptomatic Bacteriuria in Diabetic and Non Diabetic Female Patients Attending a Tertiary Care Hospital
The aim is to study the prevalence of asymptomatic bacteriuria in diabetic and non diabetic female patients attending a tertiary care hospital. This study was conducted in a tertiary care hospital from July 2015 to Decem...
Comparison of Serum Uric Acid Level and Coronary Artery Calcium Score
Abstract: The aim of the study was to evaluate the interrelation between serum uric acid and artery calcification in asymptomatic coronary artery disease subjects. Dialysis patients display an increased mortality which...
Infection Rate of Cryptosporidium parvum among Diarrhea Children in Ibadan, Oyo State, Nigeria
Cryptosporidiosis is an important major cause of enteric parasitic infection among infants and children in developing countries with morbidity and mortality especially among immunocompetent individuals. This study was c...
Study on Bone Marrow Profile of Patients with Pancytopenia in a Tertiary Care Centre
Abstract: Pancytopenia is a common haematological entity that is characterized by the simultaneous presence of anemia, leukopenia and thrombocytopenia. A multitude of disorder primarily or secondarily affecting the bone...
An Interventional Study Showing Effect of Yoga on Serum Cortisol of Depression Patients Attending Psychiatric OPD, SMS Hospital, Jaipur
Depression is a major cause of morbidity worldwide. WHO ranked it fourth in a list of most urgent health problems of the world? Depression is twice as common in women as in men and is well known to be associated with hyp...