A COMPARISON OF PAP SMEAR, COLPOSCOPY AND COLPOSCOPY DIRECTED BIOPSY IN EVALUATION OF UNHEALTHY CERVIX
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2015, Vol 4, Issue 21
Abstract
[b]OBJECTIVES[/b]: To obtain Colposcopic directed biopsy from suspicious and abnormal areas on the cervix, to correlate the findings in women with unhealthy cervix by Papsmear, Colposcopy and Histopathological findings and to assess the utility of Colposcopy in detecting carcinoma of the cervix in its preinvasive stage. [b]STUDY DESIGN[/b]: Observational study over a period of one and half years.Setting: Study was carried out in the Out Patient Department (OPD) at the Kempegowda institute of medical Sciences. Bangalore. [b]SAMPLE SIZE[/b]: One hundred women. [b]METHODS[/b]: 100 patients who were aged between 18- 65 yrs and had clinically unhealthy cervix, were subjected to pap smear, colposcopy and colposcopic directed biopsies and the findings were noted. All the patients underwent both the acetic acid and the Schiller’s test before they were subjected to colposcopic directed biopsies. The biopsies were taken from the acetowhite areas and the iodine negative areas. The sensitivity, specificity, positive predictive value, negative predictive value and accuracy were calculated for pap smear colposcopy with colpscopic directed biopsy as the gold standard. [b]RESULTS[/b]:The sensitivity and specificity of Pap smear was found to be 50% and90% respectively and that of colposcopy 85% and 83.75% respectively. Colposcopy showed higher sensitivity and lower specificity and higher positive predictive value compared to Pap smear. The accuracy of colposcopy was higher than that of Pap smear. [b]CONCLUSION[/b]:Colposcopy is useful in detecting premalignant and malignant lesions of the cervix. Colposcopy and cytology used together in patients of cervical lesions have a relatively higher chance of detecting squamous intraepithelial lesions/malignancy as compared to either procedure when performed alone.
Authors and Affiliations
Savitha T. S. , Waghmare Sapna
Keywords
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- EP ID EP138169
- DOI 10.14260/jemds/2015/524
- Views 68
- Downloads 0
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