RISK FACTORS FOR DEVELOPMENT OF LYMPHEDEMA FOLLOWING BREAST CANCER TREATMENT: A RETROSPECTIVE STUDY
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2015, Vol 4, Issue 46
Abstract
[b] OBJECTIVES[/b]: The aim and objective of this study is to identify the factors associated with secondary lymphedema after breast cancer treatment.[b] BACKGROUND:[/b] Lymphedema of the arm is a complication of breast cancer treatment that affects 2-40% of breast cancer survivors. The pathophysiology of lymphedema following breast cancer treatment is poorly understood, probably suggesting a multifactor nature. As the breast cancer survival rate increases, lymphedema will potentially impact more women. [b]METHODS:[/b] A retrospective study of 506 patients who underwent modified radical mastectomy for breast cancer in our institute between January 2009 to December 2013. Available follow up period varied from 8 months to 5 years. [b]RESULTS: [/b]Out of 506 patients studied 70 patients developed lymphedema. Lymphedema was associated with younger age group at diagnosis, positive history of hypertension, obesity, Involvement of more than 4 lymph nodes, higher TNM stage, and axillary RT. [b]CONCLUSION[/b]: Post treatment lymphedema continues to be a significant problem following breast cancer therapy. Combination of axillary dissection and axillary radiotherapy should be avoided whenever feasible to avoid lymphedema. Control of hypertension and weight reduction via dietary and exercise interventions may be most effective preventive and therapeutic measures.
Authors and Affiliations
Madhusudan A. , Ashwin Hebbar , Sunil H, Mohammed Arif
Keywords
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