3-[(2-chloroquinolin-3-yl)methyl]quinazolin-4(3H)-ones as potential larvicidal agents
Journal Title: Pakistan Journal of Pharmaceutical Sciences - Year 2013, Vol 26, Issue 4
Abstract
The larvicidal effect of series of 3-[(2-chloroquinolin-3-yl)methyl] uinazolin-4(3H)-ones, 5a-e, against Chironomus tentans Fabricius has been investigated. The results showed that tested compounds demonstrated strong larvicidal activity, and caused high percentage of mortality after 24 h at the doses of 40-100 g/ml, especially in the case of 3-[(2-chloro-8-methyquinolin-3-yl)methyl]quinazolin-4(3H)-one, 5b, that act as a promising larvicidal agent.
Authors and Affiliations
Selvaraj Roopan, Fazlur-Rahman , Nawaz Khan, Jong Jin
Keywords
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