A REVIEW ON LATEST TRENDS IN ONCHO NANOTECHNOLOGY
Journal Title: International Journal of Pharmaceutical Development & Technology - Year 2013, Vol 3, Issue 2
Abstract
Amongst various cancer therapies, chemotherapy is one of major treatment modalities along with debulking surgery. Major challenges in chemotherapy are linked to toxicity on healthy proliferating cells and multidrug resistance against anticancer drugs. However, these approaches failed because of significant heterogeneity in both solid tumour cell types and cell surface markers. However, in most tumors the pH gradient is reversed. The low pH in tumour extra cellular space or in various sub cellular organelles is a significant signal for targeting which is the basis for the pH targeting nanotechnology a novel anticancer drug delivery .This abstract highlights recent progress of the pH sensitive tumour targeting nano carriers.
Authors and Affiliations
Chandrasekhar P , Shahid Mohammad S , Subhashis Debnath , Lava Kumar M , Niranjan Babu M
Keywords
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