A study of histopathological changes in burn deaths at civil hospital AhmedabadGujarat
Journal Title: International Journal Of Research In Medicine - Year 2014, Vol 3, Issue 1
Abstract
BACKGROUND: Burns are the second leading cause of accidental death. Burn injuries are very common in developing countries due to high population density, domestic accidents, poverty, illiteracy, lack of appropriate safety measures, and negligence in certain working environment. Our aim is to examine histopathology in different organ and skin affected due to burn. MATERIALS AND METHODS: A cross-sectional descriptive study was conducted over a period of one year from May 2007 to April 2008 in 47 autopsies of burn. Microscopic examination of lung, liver, kidney, spleen, heart, brain and skin were performed with hematoxylin and Eosin staining in autopsy section of histopathology department, BJ Medical College, Ahmedabad, Gujarat. RESULTS: Female to male ratio is 1:1.24. Most affected age group is 21 to 40 years. 21 to 30 years of female predominantly affected due to thermal burn. 33.3% skin present with epidermal nuclear elongation, intra epidermal separation. More than half of lung specimens show congestion, hemorrhage and oedema in alveolar space. Histopathology reveals necrosis (46.2%), fatty changes (38.5%) and infarction (30.8%) in liver and kidney present with necrosis of cortex (61.5%), Cloudy degeneration (53.9%) and infective nephritis (46.2%). CONCLUSION: Major Proportion of economically active population affected due to burn. Younger age female more prone to injured in domestic fire. Skin changes are specific in electric burn. Congestion, oedema, hemorrhage and necrosis frequently present in the various organs were insignificant. We believe that these finding are not specific and are seen in many other terminal diseases.
Authors and Affiliations
Mital R. Rathod1* , Hansa Goswami2 , Dharmendra Jankar3
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