A STUDY OF VOICE CHANGES IN SPASMODIC DYSPHONIA AFTER BOTULINUM THERAPY
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2016, Vol 5, Issue 22
Abstract
BACKGROUND Spasmodic dysphonia is a neurological disorder, which can give the voice a strained quality. There is currently no cure for spasmodic dysphonia. The most common treatment for spasmodic dysphonia is the injection of botulinum toxin. METHODS Botulinum toxin A injection was performed in 10 patients with adductor spasmodic dysphonia. Voice handicap index scoring and voice analysis was done pre- and post-injection. Fundamental frequency, standard deviation of fundamental frequency, jitter, shimmer, mean phonation time and voice noise energy was studied in voice analysis. These voice parameters were measured from sustained phonation of vowel /a/. RESULTS Results of study indicated, a) Spasmodic dysphonia patients had high mean values for voice handicap index score and all voice parameters. b) All parameters were reduced significantly post botulinum therapy, but remained higher than their normal value. c) All voice parameters except jitter showed strong positive correlation with voice handicap index in all domains. Jitter showed moderate positive correlation with total score, physical and emotional domain and strong positive correlation with functional domain. CONCLUSION Botulinum toxin A injection improves voice in cases of spasmodic dysphonia, significantly still post procedure voice does not return to normal
Authors and Affiliations
Sanajeet Singh, Arun , Suresh , Jeevan , Manoj Kanzhuly, Nikhil , Kamal Joshi , Abhipsa
Keywords
Related Articles
- EP ID EP154365
- DOI 10.14260/jemds/2016/268
- Views 98
- Downloads 0
EFFICIENCY OF TOPICAL PHENYTOIN ON HEALING IN DIABETIC ULCER: A RANDOMIZED CONTROL TRIAL
Diabetic foot ulcers are the major complication of diabetes mellitus; 15% of diabetic people suffer from foot ulcers. Phenytoin is used as a topical application in many studies on diabetic foot ulcers and it is f...
ROLE OF SERUM ASSISTED CONJUNCTIVAL AUTOGRAFT IN THE MANAGEMENT OF PRIMARY PTERYGIUM
BACKGROUND Objective- To evaluate the outcome of serum assisted conjunctival autograft in patients with primary pterygium. MATERIALS AND METHODS An uncontrolled clinical trial was done over a period of 18 months, where 8...
RISK FACTORS OF PRIMARY LUNG CANCER AMONG FEMALES
BACKGROUND Lung cancer is fast emerging to be a leading cause of cancer mortality, both in developing and developed countries alike. Despite the fact that tobacco smoke is a predominant cause, its increasing incidences a...
DERMATOFIBROSARCOMA PROTUBERANS: CASE REPORT WITH REVIEW OF LITERATURE
Dermatofibrosarcoma Protuberans is an uncommon clinical entity. Dermatofibrosarcoma Protuberans (DFSP) is a sarcoma that arises from the dermis and invades the deeper tissues. It is a locally aggressive which rarely...
SMALL BOWEL OBSTRUTION DUE TO MECKEL’S DIVERTICULUM: A CASE REPORT
Meckel’s Diverticulum is the most common congenital anomaly of the intestine. Its common complications include hemorrhage, inflammation, and intestinal obstruction. Small bowel obstruction due to Meckel’s Dive...