ANALYSIS OF TUMOUR LENGTH AND CLINICOPATHOLOGICAL FEATURES IN CARCINOMA OESOPHAGUS
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2016, Vol 5, Issue 49
Abstract
Even with multidisciplinary team approach, the prognosis of Oesophageal Cancer (EC) has not significantly changed. Studies are required to explore the other prognostic factors, which might alter the outcome. Our study aims at correlating the oesophageal tumour length with stage of the disease and analyse the clinicopathological features. METHODS 150 patients with oesophageal carcinoma (ca) who underwent curative surgery without neoadjuvant chemotherapy and/or radiotherapy are included in the study. Formalin fixed oesophageal tumour length was measured. Tumour length was analysed with respect to overall stage, T stage and N stage of the disease. Clinicopathological characteristics were studied. RESULTS From our study correlating tumour length with stage and lymph node involvement, it is observed that there is no linear association with stage of the disease. Squamous cell carcinoma is the predominant histology and lower third was the site most affected. Even though most of the patients still present at an advanced stage, patients with adenocarcinoma presented earlier than squamous cell carcinoma patients. CONCLUSION As there is no proportionate increase in stage of disease with increase in length of tumour, oesophageal tumour length may not be an appropriate prognostic factor. Further well planned studies might bring more evidence on this aspect with respect to impact of tumour length on survival.
Authors and Affiliations
Pampanagouda , Sailaja , Veerendrakumar Veeraiah
Keywords
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- EP ID EP149345
- DOI 10.14260/jemds/2016/730
- Views 72
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