Antimalarial and insecticidal activities of newly synthesized derivatives of Benzimidazole
Journal Title: Pakistan Journal of Pharmaceutical Sciences - Year 2015, Vol 28, Issue 6
Abstract
The bioactive benzimidazole and corresponding substituted phenacyl halides has been synthesized (11) new derivatives out of three compounds 8, 10 and 11 were found to inhibit the Plasmodium falciparum moderately after 72 hours of incubation hence acting as antimalarial agents. While these derivatives were exhibited negligible insecticidal activity too when analyzed by impregnated filter paper method.
Authors and Affiliations
Arfa Kamil , Shamim Akhter , Maryam Ahmed , Ghazala H. Rizwani , Sohail Hassan , Sabahat Naeem , Sarwat Jahan , Raheela Khursheed , Hina Zahid
Keywords
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