Antimicrobial and antioxidant activities and chemical characterization of essential oils of Thymus vulgaris, Rosmarinus officinalis, and Origanum majorana from northeastern México
Journal Title: Pakistan Journal of Pharmaceutical Sciences - Year 2015, Vol 28, Issue 1
Abstract
There have been no reports of antifungal activity and composition of extracts from Thymus vulgaris, Rosmarinus officinalis or Origanum majorana from northeastern México. Antifungal activity of these oils against Trichophyton rubrum, Trichophyton tonsurans, Trichophyton mentagrophytes, Microsporum gypseum, Microsporum canis and Epidermophyton floccosum was measured by diffusion assay. Additionally, antibacterial and antioxidant activities were evaluated. Antibacterial activity against Staphylococcus aureus and Streptococcus pyogenes was examined by microdilution. Antioxidant activity was assessed by 2,2-difenil-1-picrilhidracil reduction test. The plant oils were characterized by both GC/MS and GC/FID. Oils of T. vulgaris and O. majorana showed growth inhibition activity against dermatophytes, especially T. vulgaris oil, which completely inhibited growth of all tested dermatophytes. The oils also showed bioactivity against bacteria, with minimum inhibitory concentration (MIC) values between 62.5 and 500 g/mL. The antioxidant activity of the oils was low, with effective concentration (EC50) values >250g/mL. The major components in the oils were as follows: T. vulgaris, o-cymene, -terpinene, thymol and carvacrol; R. officinalis, terpinen-4-ol and 1,8-cineole; O. majorana, terpinen-4-ol and thymol.
Authors and Affiliations
Laura Guerra-Boone , Rocío Alvarez-Román , Ricardo Salazar-Aranda , Anabel Torres-Cirio , Verónica Mayela Rivas-Galindo , Noemí Waksman de Torres , Gloria González , Luis Alejandro Pérez-López
Keywords
Related Articles
- EP ID EP153022
- DOI -
- Views 116
- Downloads 0
Exploiting the interaction of polymethacrylates with iron oxide for the enhancement of mucoadhesive strength
Abstract: The present investigation was aimed at preparation of polymethacrylate(s)- iron oxide conjugates and to evaluate mucoadhesive performance using texture analyzer. Eudragit RL-iron oxide or Eudragit RS-ir...
Distribution and clinical characteristics of pathogenic bacteria causing catheter-related bloodstream infections
This paper on analysis pathogenic bacterial distribution of central veins Catheter-related Blood-Stream Infection (CRBS) and clinical features of different infection. Ninety-one patients with CRBSI were selected, t...
Clinical evaluation of unani ear drops herbotic for earache
An ear infection (acute otitis media) is most often a bacterial or viral infection that affects the middle ear. Children as compared to adults are more are prone to infections. A study has been conducted on 200 pat...
Antioxidant activity of simvastatin prevents ifosfamide-induced nephrotoxicity
Ifosfamide is an anticancer agent used largely in treatment of solid tumors. The mainstay dose-limiting toxicity of ifosfamide is nephrotoxicity. This is largely believde to be a result of ifosfamide-induced oxidat...
Antimicrobial, antitumor and brine shrimp lethality assay of Ranunculus arvensis L. extracts
To investigate the antitumor activity, brine shrimp lethality assay, antibacterial and antifungal activity of Methanol Extract (ME), Water Extract (WE), Acetone Extract (AE), Chloroform Extract (CE), Methanol-Water...