CLINICAL PROFILE OF HEPATITIS B VIRUS INFECTION IN PATIENTS ATTENDING TERTIARY CARE CENTRE IN EASTERN INDIA
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2016, Vol 5, Issue 37
Abstract
AIMS A cross-sectional Study, performed in two tertiary care referral clinics to determine the clinical profile of Hepatitis B patients attending tertiary care centres in Eastern India. Patients were segregated as symptomatic and asymptomatic. RESULTS The age of the patients varied from 16-76 years. The mean age of the patients was found to be 34.54 years with a standard deviation of 13.53 years. Only 16% of the patients were symptomatic on presentation. Common clinical features were nausea (22%), splenomegaly (22%), jaundice (13%), abdominal pain (19%) and hepatomegaly (10%). Bilirubin and alanine transaminase (ALT) levels were significantly higher in symptomatic patients. Strong significant positive correlation found between AST and Bilirubin (r=0.346), p value=0.0004; ALT and Bilirubin are positively correlated (r=0.298), p value=0.003; ALT and AST are positively correlated(r=0.710), p value=<0.0001; ALT and Albumin are positively correlated(r=0.216), p value=0.031(Moderate significant correlation) in the entire study population. CONCLUSION The current study demonstrates the clinical and biochemical features that a hepatitis B infected patient may present with. Most of the patients with hepatitis B are asymptomatic (84%) on presentation. To our knowledge, this is the first paper reported from Eastern India in recent times which has shed a light on the differences in the pattern of the biochemical parameters among the symptomatic and asymptomatic hepatitis B infected patients.
Authors and Affiliations
Champa , Sekhar , Kingshuk
Keywords
Related Articles
- EP ID EP128564
- DOI 10.14260/jemds/2016/518
- Views 92
- Downloads 0
A STUDY OF LIPID PROFILE AND ASSESSMENT OF CARDIOVASCULAR RISK IN SUBCLINICAL HYPOTHYROIDISM
BACKGROUND Studies on association between subclinical hypothyroidism and lipid profile have produced conflicting results. The assessment of cardiovascular risk in subclinical hypothyroid patients is rare in Indian scenar...
EFFICACY OF EPIDURAL 0.5% ROPIVACAINE WITH FENTANYL COMPARED TO EPIDURAL 0.5% BUPIVACAINE WITH FENTANYL FOR LSCS
BACKGROUND The combination of local anaesthetics with adjuvants is getting more popular for better post-operative analgesia. Ropivacaine, senantiomer produces neural blockade with less cardiovascular toxicity than bupiva...
APPENDICULAR MASS- A PROSPECTIVE AND COMPARATIVE STUDY
BACKGROUND Acute appendicitis remains the commonest cause of acute abdomen in teenagers requiring surgical intervention. Patients presenting late in the course of acute appendicitis are complicated by the development of...
DEXMEDETOMIDINE AS A SOLE ANAESTHETIC AGENT IN NEUROSURGICAL PROCEDURES
BACKGROUND Dexmedetomidine is an alpha-2 agonist gaining popularity in neurosurgery due to its unique properties as a sedative, anxiolytic and anaesthetic sparing effects without respiratory depression. We designed this...
ANTIOXIDANT AND ANTIMICROBIAL ACTIVITY OF PROPOLIS
BACKGROUND In the present scenario of increasing bacterial drug resistance where the selection of antibiotics available becomes a limiting factor, botanicals (natural products) with antioxidant properties which can stimu...