CLINICAL PROFILE OF MEDIASTINAL MASSES
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2016, Vol 5, Issue 53
Abstract
ROUND Mediastinal masses are relatively uncommon and continue to be an interesting diagnostic and therapeutic challenge to pulmonologists and thoracic surgeons. Mediastinal tumours represent 3% of tumours seen within chest. This study is chosen with an aim to assess the clinical profile of mediastinal masses. AIM To study the clinical, radiological, pathological and aetiological profile of mediastinal masses. MATERIALS AND METHODS This was a two-year prospective study conducted at Govt. Chest Hospital, Andhra Medical College, Visakhapatnam, Andhra Pradesh; 30 patients were enrolled into study who fulfilled the inclusion criteria. After detailed history and physical examination, the patients were subjected to various necessary investigations to arrive at aetiological diagnosis. Results were analysed as percentages and compared with other studies. RESULTS The mean age of presentation was 43.6 years with a male-to-female ratio of 3.16:1. Cough, chest pain and breathlessness were most common presenting symptoms. Pallor was the most common presenting sign; 80% of the cases were anterior mediastinal masses, 13% posterior and 7% were middle mediastinal masses; 70% of the cases were malignant and 30% of cases were benign. The most common aetiology was lymphoma (30% of cases) followed by lung cancer and thymoma. Other less common causes were teratoma, bronchogenic cysts, neurofibroma, mediastinal lipomatosis, synovial sarcoma, intrathoracic aneurysm and metastasis. In 2 cases, aetiology was not known. CONCLUSION Mediastinal masses are usually symptomatic at presentation. Malignant lesions were more common and they present with symptoms of mediastinal obstruction. Lymphoma was the most frequent primary mediastinal mass followed by lung cancer and thymoma.
Authors and Affiliations
Gayatri Yellapu, Usha Numballa, Ramesh , Joshua , Narayana
Keywords
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- EP ID EP138906
- DOI 10.14260/jemds/2016/819
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