COEXISTENCE OF CUTANEOUS MUCORMYCOSIS AND SCROFULODERMA IN AN IMMUNODEFICIENT CHILD
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2016, Vol 5, Issue 8
Abstract
Severe Combined Immunodeficiency (SCID) is a genetic disorder characterised by the disturbed development of functional T cells and B cells caused by numerous genetic mutations. (1) These patients are extremely vulnerable to infectious diseases and early death. (1) A 1-year-old child, known case of SCID since 8 months of age, presented with septic shock. He had a swelling on the left hand for 1 month and over left hand, which was a prior site of IV cannulation and swelling over axilla since 6 months. The child received multiple blood transfusions, though no bone marrow transplant was done. We entertained a differential diagnosis of cutaneous tuberculosis, atypical mycobacterial infection, deep fungal infection and foreign body granuloma for the left hand nodule. We thought of scrofuloderma with lymphadenopathy as a diagnosis for the axillary lesion. Biopsy of the hand lesion-multiple broad aseptate hyphae with granulomatous infiltrates suggesting mucormycosis. FNAC of axillary lymph node-necrotising lymphadenitis with AFB positive. Chest X-ray HRCT-PCP Pneumonia. He was started on IV Amphotericin-B.
Authors and Affiliations
Mahalakshmi , Gayathri , Maharaja , Adikrishnan , Sudha
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