COMPARISON OF SOCIODEMOGRAPHIC AND CLINICAL VARIABLES IN SCHIZOPHRENICS WITH AND WITHOUT SUBSTANCE ABUSE
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2016, Vol 5, Issue 66
Abstract
BACKGROUND Substance abuse is associated with poor outcome in schizophrenia patients. Alcohol and cannabis were reported to be most commonly abused substances in schizophrenics. Great care is needed to manage these patients. Sociodemographic and clinical data from India is sparse and therefore the need for this study. MATERIALS AND METHODS Patients who gave written informed consent and met inclusion and exclusion criteria were taken into study. They were administered sociodemographic proforma, clinical profile sheet, and substance abuse proforma. Data was subjected to statistical analysis. RESULTS Mean age of substance abusers was 27.96 yrs. and of non-abusers group was 32.68 yrs. Non-abusers group had a later age of onset of schizophrenia compared to the substance abusers group (mean age at onset: 25.56 vs. 22.88 yrs.). Duration of schizophrenia in substance abusers was shorter compared to non-abusers (mean duration in months: 65.00 vs. 89.88). Onset of schizophrenia was acute in 2 and insidious in 21 patients of non-abusers group. Commonest subtype of schizophrenia was paranoid in 18 and 20 among substance abusers and non-abusers respectively. Family history of substance abuse was present in 12 substance abusers as compared to only 3 of non-abusers. Among substance abusers 60% abused alcohol, 28% cannabis, 28% opioids, and 16% were polysubstance abusers. Alcohol abuse had a later age of onset than both cannabis and opioids. CONCLUSION Substance abusing schizophrenics were younger than non-abusing. 60% of patients had completed middle school and more than half had semiskilled jobs. Majority were married. Substance abusers had earlier onset and shorter duration of schizophrenia than non-abusers. Most patients had paranoid schizophrenia and insidious onset of illness. Alcohol was commonest abused substance. Age of onset for alcohol abuse was higher than that for cannabis.
Authors and Affiliations
Manjunath , Pravin
Keywords
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