Current Concepts on the Etiology and Treatment Of Infectious arthritis
Journal Title: IOSR Journal of Pharmacy (IOSRPHR) - Year 2014, Vol 4, Issue 2
Abstract
Infectious arthritis is an important joint infection in rheumatology emergency. Infection is usually hematogenously acquired during overt or occult bacteremia. Septic arthritis is an unusual complication of arthroscopy or arthroscopic reconstruction of knee surgery. Health care acquired infections are associated with higher mortality rate. Up to 50% of patients reporting decreased joint function or mobility. Any organism can cause infectious arthritis include: gonococcus, S.aureus, MRSA, streptococci, mycobacteria, fungi and virus. Diagnosis, treatment, prognosis of infectious arthritis mainly dependent on the identity of infecting pathogen and host factors. Therapy of infectious arthritis is with antimicrobials with ability to penetrate into synovial fluid, e.g. nafcillin, clindamycin, vancomycin, and cephalosprorins .Oral ciprofloxacin is the drug of choice for known susceptible pathogens. Antifungal include: amphotericin B, flucytocine, and newer extended spectrum triazole.
Authors and Affiliations
Atiqah C. Abdullah , Murtaza Mustafa , Muhammad Iftikhar 3 , Malik J. Shah
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