Erythrocyte functional status and lipid profile of coal mine workers of West Bengal, India
Journal Title: Progress in Health Sciences - Year 2014, Vol 4, Issue 2
Abstract
Purpose: Despite people suffering from several forms of ill health, constant exposure to toxic wastes and chronic diseases as a result of mining, there is a tragic gap in the availability of ‘scientific’ studies and data on the health hazards of mining in India. This study was proposed to understand better the relationship between occupational exposure to coal, blood lipid profiles and red blood cell (RBC) functional status of coal workers. Materials and methods: Blood samples were obtained from coal miners (n=32) of an underground mine in West Bengal. Blood lipid profiles and RBC functional status were determined. Students’ t-test and Pearson correlation analyses were completed to analyze the data. Results: Compared to the control subjects, significantly higher levels of cholesterol (p<0.01), triglycerides (p<0.01), LDL (p<0.001), and VLDL (p<0.001) were observed in coal miners. HDL, Hb, Na+-K+ATPase and SOD activity were significantly (p<0.001) lower in coal miners, whereas MDA levels (p<0.001) and osmotic fragility in coal miners were increased significantly (p<0.01). Conclusions: Our study indicates that elevated MDA and antioxidant insufficiency caused disruption in the structural integrity of erythrocyte, which may be a pathophysiological mechanism in the progression of disease in coal miners. Also, cardiovascular disease risk factors were more prevalent in the coal miners.
Authors and Affiliations
SK. Prasad, A. Bhattacharjee, P. Bandyopadhyay, S. Pal, AK. Syamal
Keywords
Related Articles
- EP ID EP94743
- DOI -
- Views 101
- Downloads 0
Transmucosal in addition to transdermal fentanyl, administered in exacerbations of cancer pain, does not change the emotional status of patients
Introduction: Opioids, regardless of the route of administration, are essential analgesics for the treatment of cancer pain. The transmucosal route of fentanyl administration is a relatively new but widely used technique...
University students' problem-solving behaviors and exposure to dating abuse in their romantic relationship
Purpose: To examine problem solving behaviors and exposure to dating abuse of the students studying in the Nursing Department, in their romantic relationships. Materials and methods: This research was conducted a...
The Health Related Quality of Life aspects in chronic rheumatic diseases
Purpose: The aim of the study is comparative analyze the Health Related Quality of Life (HRQOL); effect of social-demographic factors on quality of life also taking into account four domains and effect of the duration of...
Stigma of people living with HIV/AIDS
A specific character of HIV/AIDS has caused numerous complications either medical, legal or social. HIV infection exposes its carriers to frequent acts of intolerance or stigma by the healthy part of the population. Nega...
Human bronchial epithelial cells as a good control for evaluation potential therapeutic Notch signaling in non-small cell lung cancer
<b>Purpose</b>: Notch signaling is often deregulated in non-small cell lung cancer (NSCLC), but little is known about the initial endogenous mRNA status of Notch ligands and receptors. Therefore, the aim of this study wa...