HISTOPATHOLOGICAL EVALUATION OF ENDOSCOPIC BIOPSIES IN PATIENTS WITH LESIONAL GASTROINTESTINAL TRACT DISORDERS
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2016, Vol 5, Issue 1
Abstract
BACKGROUND Histopathological examination of endoscopic biopsies is the easiest way to diagnose the gastro intestinal tract (GIT) disorders. This study deals with histopathological evaluation of 60 Gastrointestinal Tract (GIT) endoscopic biopsies carried out between January 2014 to February 2015. MATERIALS AND METHODS Flexible endoscope was used to retrieve biopsy material, which was then fixed with 10% formalin and further processed with Hematoxylin and Eosin (H and E), Periodic Acid–Schiff (PAS), Giemsa, Acid-Fast Stain (AFS), Alcian Blue and examined by histopathologists. RESULTS Stomach (45 cases) was the most common site for biopsy. Chronic non-specific gastritis was the most common lesion diagnosed in the stomach and in GIT (24 cases). Colon was the second most common site for biopsy. Colitis/proctitis was diagnosed in 6 out of 12 colonic biopsies. Malignant lesions diagnosed were 8 adenocarcinoma of stomach, 2 squamous cell carcinoma of esophagus and 1 adenocarcinoma colon. Out of all 60 cases 48 (80%) were non-neoplastic and 12 (20%) were neoplastic cases. CONCLUSION We conclude that endoscopic biopsy for diagnosing GIT lesions is the gold standard and indispensable for diagnosis and management.
Authors and Affiliations
Anand Patil , Maraudavanan Ramachandran, Kumar Mohan, Kaviraj Mahadevan, Balamurugan Rangasamy
Keywords
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- EP ID EP128467
- DOI 10.14260/jemds/2016/1
- Views 79
- Downloads 0
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