PATHOLOGICAL SPECTRUM OF CONGENITAL ANOMALIES OF THE GASTROINTESTINAL TRACT- A 5 YEAR STUDY AT A PAEDIATRIC REFERRAL CENTRE
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2013, Vol 2, Issue 25
Abstract
[b] INTRODUCTION[/b]: Congenital anomalies of gastrointestinal tract occur from oesophagus upto anorectum as a result of abnormal embryogenesis. Specific patterns of malformations of gastrointestinal tract include stenosis and atresia, duplications, abnormal rotation and fixation, abdominal defects and others associated with persistence of embryonic structures (e.g. Meckel's diverticulum), or abnormalities in its cellular components (e.g. nerves in Hirschsprung's disease). These disorders primarily result in symptoms of intestinal obstruction, effects on surrounding structures or of associated anomalies. Early diagnosis is therefore very vital. AIM: To study the clinical presentation, radiological features, gross and histopathology of congenital anomalies of G.I.T. [b]MATERIAL AND METHODS[/b]: Surgical specimens collected were sent to the department of pathology for gross and histopathological confirmation of diagnosis. The specimens were processed routinely and H & E stained slides studied. [b]RESULTS[/b]: Out of 2996 specimens, 286 were found to be of congenital anomalies of G.I.T. With a sex ratio of 3:1Hirschsprung’s disease was commonest 50.34%, Omphalomesenteric duct remnants 16.78%, followed by intestinal atresia 10.13% [b]CONCLUSION[/b]: Congenital anomalies of gastrointestinal tract are a cause of significant mortality and Morbidity in paediatric age group. Though radiodiagnosis is the preliminary diagnostic modality, gross and histopathological examinations are essential to confirm the diagnosis
Authors and Affiliations
Ramani M, Radhika Krishna, Geeta K, Ramesh Reddy, Sreenivas Reddy, Soumya E, Puja Deshmukh, Sandhya Rani
Keywords
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- EP ID EP143379
- DOI 10.14260/jemds/867
- Views 73
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