PHARMACEUTICAL APPROACH TO SUPRAMOLECULAR CHEMISTRY – A COMPREHENSIVE REVIEW
Journal Title: International Journal of Pharmaceutical Development & Technology - Year 2013, Vol 3, Issue 1
Abstract
Supramolecular chemistry refers to the area of chemistry beyond the molecules and focuses on the chemical systems made up of a discrete number of assembled molecular sub-units or components. A Super molecule is an organized, complex entity that is created from the association of two or more chemical species held together by intermolecular forces. There is a wide scope for supramolecular chemistry in improving the characteristics of chemical entities. The technique is pharmaceutically used to increase the bioavailability, solubility and stability of the active pharmaceutical ingredients by formation of complexes, inclusion complexes and co crystals. This article highlights the role of supramolecular chemistry in design and synthesis of novel pharmaceutical multiple component crystalline phases.
Authors and Affiliations
S. Vijayaraj , A. Saravana Kumar
Keywords
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