Preliminary phytochemical screening, antimicrobial and antioxidant activities of Euphorbia milli

Journal Title: Pakistan Journal of Pharmaceutical Sciences - Year 2014, Vol 27, Issue 4

Abstract

 Euphorbia milii is a Pakistani herb used for various infectious diseases. In this study we have carried out phytochemical, antibacterial and antioxidant investigation of different extracts/fractions. Phytochemical studies showed the presence of cardiac glycosides, steroids/phytosterols, anthocyanin, proteins, terpenoids, flavonoids and tannins. Susceptibility testing by well diffusion assay of its chloroform and methanol fractions revealed good antimicrobial activity against Klebsiella pneumonia and Staph epidermis. Ethyl acetate fraction of roots also exhibited considerable antimicrobial activity against most of tested pathogens. Various fractions (Hexane, chloroform, methanol and water) of E. milii were screen for their antioxidant potential using DPPH radical scavenging assay at different concentrations among these, chloroform fraction exhibited good scavenging activity. The IR spectroscopy of the various extracts/fractions indicated the presence of OH, saturated CH stretching, C=C, C=O, NO2, C-N, Ar-O, C-O- and R-O-Stretching respectively. The findings provide helpful evidence for the use of E. milii in traditional medicines.

Authors and Affiliations

Abdur Rauf , Ajmal Khan , Nizam Uddin , Muhammad Akram , Mohammad Arfan , Ghias Uddin , Muhammad Qaisar

Keywords

Related Articles

 Selective extraction of berberine and palmatine from Huangbai powder

 Berberine and palmatine are two of the main bioactive components in Huangbai, a major Chinese medicinal herb. The current methods to extract these compounds usually involving the usage of inorganic acid and base, a...

 High fat diet induced insulin resistance and elevated retinol binding protein 4 in female rats; treatment and protection with Berberis vulgaris extract and vitamin A

 This research was conducted to investigate two main aims; the first aim was to find if there is a relationship between insulin resistance (IR) and retinol binding protein 4 (RBP4). The second aim was to use berberi...

 Moisturizing effect of stable cream containing Crocus sativus extracts

 The present study is about to prepare stable cream of water-in-oil emulsion containing extracts of Crocus sativus against its base (without extracts) taken as control, to determine its stability on different storag...

 Antimicrobial and antioxidant screening of N¢-substituted sulphonyl and benzoyl derivatives of 4-Pyridine carboxylic acid hydrazide

 In this research program, the antibacterial, antifungal and antioxidant activities of six Nʹ-substituted sulfonyl and benzoyl derivatives of lead molecule PCH were reported. Out of these compounds, sulphonyl deriva...

 Influence of Artemisia annua extract derivatives on Proliferation, apoptosis and metastasis of osteosarcoma cells

 Regarding the Artemisia annua extract derivatives called dihydroarteminin (DHA) as the object, we studied about its influence to the proliferation, apoptosis and metastasis of human osteosarcoma cells. First, we cu...

Download PDF file
  • EP ID EP110536
  • DOI -
  • Views 117
  • Downloads 0

How To Cite

Abdur Rauf, Ajmal Khan, Nizam Uddin, Muhammad Akram, Mohammad Arfan, Ghias Uddin, Muhammad Qaisar (2014).  Preliminary phytochemical screening, antimicrobial and antioxidant activities of Euphorbia milli. Pakistan Journal of Pharmaceutical Sciences, 27(4), 947-951. https://europub.co.uk./articles/-A-110536