Role of Medicinal Plants in the Treatment of Alzheimer’s Disease: A Review
Journal Title: Scholars Academic Journal of Pharmacy - Year 2013, Vol 2, Issue 1
Abstract
Abstract: Alzheimer’s disease (AD) is an age related neuro degenerative disorder that is characterized by a progressive loss of memory and deterioration of higher cognitive functions. The brain of an individual with AD exhibits extracellular plaques of aggregated β-amyloid protein (Aβ), intracellular neurofibrillary tangles that contain hyperphosphorylated tau protein and a profound loss of basal forebrain cholinergic neurons that innervate the hippocampus and the neocortex. There are several studies and alternative therapies which offer ways to slow the onset and progression of AD in some patients. Many synthetic drugs because of many unwanted but unavoidable side effects have poor patient compliance. Herbal remedies for AD have become more and more popular in the recent years and not without a reason that there is a possibility to slow down the brain’s degeneration caused by Alzheimer’s with natural treatments and it has drawn the attention of the scientific community. Therefore herbal treatment is being preferred over conventional treatments. This review covers a broad spectrum of natural drugs used in AD. This topic also discuss about active constituents and specific part of the plant being used. Keywords : Alzheimer’s disease, β-amyloid protein, cholinergic neurons, patient compliance, Herbal remedies.
Authors and Affiliations
C. Rudra Maheswara Reddy , E. Venkata Naga Raju , M. Sadananda Reddy , Dr. Manjunatha P. M
Keywords
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