Spectroscopic analysis on Synthesis 1-Methyl-3-(2’-Phenylethyl)- 1H,3H-Quinazoline-2,4-dione

Journal Title: IOSR Journal of Pharmacy (IOSRPHR) - Year 2014, Vol 4, Issue 2

Abstract

 Carbomethoxy-methylanthranilic acid was synthesized from methylanthranilic acid with methylchloroformate in presence of potassium carbonate. Cyclisationreaction of Ncarbomethoxymethylanthranilic acid was performed by heating to get N-methylisatoic anhydride. 2- metholamino-N-(2’-phenylethyl) benzamidewas formed from Isatoic anhydride and phenylethyl amine. High yield of 1-methyl-3-(2’- phenylethyl)-1H,3H-quinazoline-2,4-dione alkaloids were formed by condensation and cyclisation reaction between amide and methylchloroformate. The synthesis compound was identified with the help of its melting point, C 13 NMR and H 1 NMR spectra.

Authors and Affiliations

Sushika Joshi (Mulmi)

Keywords

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  • EP ID EP121097
  • DOI -
  • Views 97
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How To Cite

Sushika Joshi (Mulmi) (2014).  Spectroscopic analysis on Synthesis 1-Methyl-3-(2’-Phenylethyl)- 1H,3H-Quinazoline-2,4-dione. IOSR Journal of Pharmacy (IOSRPHR), 4(2), 1-4. https://europub.co.uk./articles/-A-121097