STUDY OF GENITAL TUBERCULOSIS IN INFERTILE WOMEN
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2016, Vol 5, Issue 50
Abstract
AIM To determine the incidence of female Genital Tuberculosis (GTB) and to analyse clinicopathological features for GTB and comparison of Polymerase Chain Reaction (PCR), Acid Fast Bacillus (AFB) staining and Histopathology (HPR). STUDY SETTING A prospective study conducted on 50 infertile patients in the Department of Obstetrics and Gynaecology at Krishna Hospital, Karad, for a period of 2 years between December 2013 and December 2015. METHODS Patients were investigated for the presence of Mycobacterium Tuberculosis (MTB) on samples collected by endometrial curettage by PCR, AFB and HPR. Additional tests like Hysterosalpingography (HSG) Laparoscopic chromopertubation and hysteroscopy were performed if not done earlier. RESULT PCR demonstrated MTB DNA in 9 patients, and 2 were positive with AFB and HPR. Within positive patients HSG findings were suggestive of TB in 3 cases and laparoscopy in 5 cases and hysteroscopy in 4 cases. Two MTB PCR positive patients conceived spontaneously after 6 months of anti-tubercular treatment. CONCLUSION Genital tuberculosis is a diagnostic challenge if untreated it is chronic, progressive and destructive disease. Early diagnosis is crucial because once the infection damages the tubes, reverting tubal patency is very difficult. Molecular tests like DNA PCR have enabled us to detect the organism in its latent stage and initiation of treatment early in the disease can prevent many irreversible changes in the female genital tract.
Authors and Affiliations
Shrikant , Sanjay Patil, Anjali , Yamini , Kshirsagar
Keywords
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- EP ID EP138879
- DOI 10.14260/jemds/2016/741
- Views 95
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