Synthesis And Anti-Inflammatory Activity On Sulpha/Substituted Pyrazoles(1,2-Diazole)
Journal Title: IOSR Journal of Pharmacy (IOSRPHR) - Year 2013, Vol 3, Issue 8
Abstract
A Novel compound namely N1-(Nicotinoyl) 3,5 dimethyl-4-(N1-4-sulfamoylazo)-1,2-diazole has been synthesised by two step processes. Synthesis of N1-4-sulphamoylphenylhydrazono-3,5-dimethyl propane-1,3-dione and sulphonamide, which interacting with Nicotinic acid hydrazide to form final compound. The newely synthesised compound N1-(nicotinoyl)-3,5-dimethyl 4-(N-4-sulfamoyl phenyl azo) 1,2-diazoles was screened for anti-inflammatory activity
Authors and Affiliations
Rigvendra Malik, Naresh Pal,
Keywords
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