Nephroprotective Effect of Ficus Dalhousiae Miq Leaf Methanolic Extract in Albino Wistar Rats
Journal Title: International Journal of Pharma Research and Health Sciences - Year 2016, Vol 4, Issue 5
Abstract
The aim of the present study was to evaluate nephroprotective effect of Ficus dalhousiae miq leaf methanolic extract (FDLME) in Albino wistar rats.The nephrotoxicity was induced by gentamicin and Acetaminophen. Wistar albino rats weighing 150 - 200 gm were utilised for the study. The preliminary phytochemical screening of the methanolic extract of leaf showed the presence of various phytoconstituents namely alkaloids, flavanoids glycosides and sterols. The nephroprotective effect of FDLME was evident by the significant decrease in the elevated levels of serum markers such as urea, uric acid and creatinine(p<0.001) in both the experimental models.
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