Neuromyelitis Optica Spectrum Disorder (NMOSD) in a Male with Hiccups and Quadriparesis
Journal Title: International Journal of Contemporary Medical Research - Year 2018, Vol 5, Issue 11
Abstract
Introduction: Neuromyelitis-optica (NMO)/ Neuromyelitis -optica spectrum disorders(NMOSD) is an inflammatory disease of central nervous system classically characterized by acute, severe episodes of optic neuritis and longitudinally extensive transverse myelitis (LETM), usually with a relapsing course. The identification of an autoantibody exclusively detected in NMO patients against aquaporin-4 (AQP-4) has allowed identification of cases beyond the classical phenotype. Atypical cases of NMO exist in scientific literature. These cases do not present with all the symptoms. Case Report: We present a case of a 53 year old female who presented to us with quadriparesis, intractable hiccups. MRI revealed longitudinally extensive transverse myelitis and later was diagnosed as a case of NMOSD. Conclusion: Neuromyelitis optica spectrum disorders (NMOSD) are inflammatory disorders of the central nervous system characterized by severe, immune-mediated demyelination and axonal damage predominantly targeting optic nerves and spinal cord. Serum NMO-IgG antibody is specific for the diagnosis.
Authors and Affiliations
Harshpreet Singh Tuteja, Ayush Somani, Sourya Acharya, Samarth Shukla
Keywords
Related Articles
- EP ID EP432604
- DOI -
- Views 141
- Downloads 0
Study of Assessment of Plasma Homocysteine Level in Microvascular Complications of Type 2 Diabetes Mellitus
Introduction: Diabetes mellitus along with its complications bears a pertinent threat to human well being. The macrovascular and microvascular complications of diabetes contributes significantly to the mortality and morb...
Idiopathic Scrotal Calcinosis: Cytodiagnosis of Rare Entity in Two Cases
Introduction: Idiopathic calcinosis of the scrotum is a rare cutaneous disorder of benign nature characterized by the existence of multiple, hard, calcified and asymptomatic nodules within the scrotal skin that occur wit...
A Comparative Study of 2% Lignocaine vs 50% Magnesium Sulphate for Attenuation of Stress Responses to Laryngoscopy and Endotracheal Intubation
Introduction: Laryngoscopy and endotracheal intubation are essential parts of induction of general anaesthesia. Present study was undertaken to evaluate and compare the efficacy of lignocaine and magnesium sulphate for a...
Assessment of Severity and Systemic Involvement in Chronic Obstructive Pulmonary Disease by Bode Index: A Cross-Sectional Study
Introduction: BODE index is a multidimensional grading system which is based on Body mass index, airway obstruction, Dyspnoea scale, and Exercise capacity, has been in use continuously for the evaluation of chronic obstr...
Comparison of Arthroscopic Transtibial and Transportal Techniques of Anterior Cruciate Ligament (ACL) Reconstruction by a Single Bundle (SB) Quadrupled Hamstring Graft
Introduction: Ligament injuries of the knee are common in the general population, mostly occurring as a result of sports and high energy road traffic accidents. Study aimed to compare the results of Arthroscopic Transtib...